The landscape of chromosomal aberrations in breast cancer mouse models reveals driver-specific routes to tumorigenesis

Genetically engineered mouse models of cancer are useful in identifying oncogenes and tumour suppressors. Here, the authors use gene expression profiles to generate a catalogue of copy number aberrations in 45 mouse models, and compare mouse and human tumours to identify additional drivers of tumori...

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Autores principales: Uri Ben-David, Gavin Ha, Prasidda Khadka, Xin Jin, Bang Wong, Lude Franke, Todd R. Golub
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/5d7cc200cdfe438c8f082db13a6e80f0
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