SRY gene mutation in Rattus norvegicus induced by various time exposure of mobile phone

Amir A, Darwin E, Juniarto AZ. 2018. Effects of mobile phone exposure to SRY gene in Rattus norvegicus. Biodiversitas 19: 802-808. Mobile phones are low power radio devices, which transmit and receive radio frequency radiation in the microwave spectrum ranging from 900-1,800 MHz through an antenna u...

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Autores principales:	ARNI AMIR, ERYATI DARWIN, AHMAD ZULVA JUNIARTO
Formato:	article
Lenguaje:	EN
Publicado:	MBI & UNS Solo 2018
Materias:	radiation exposure snp sry gene mobile phone Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/5d84b120c99f46e8b79c62997f6d8eb1
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spelling	oai:doaj.org-article:5d84b120c99f46e8b79c62997f6d8eb12021-11-16T14:03:00ZSRY gene mutation in Rattus norvegicus induced by various time exposure of mobile phone1412-033X2085-472210.13057/biodiv/d190307https://doaj.org/article/5d84b120c99f46e8b79c62997f6d8eb12018-05-01T00:00:00Zhttps://smujo.id/biodiv/article/view/2679https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Amir A, Darwin E, Juniarto AZ. 2018. Effects of mobile phone exposure to SRY gene in Rattus norvegicus. Biodiversitas 19: 802-808. Mobile phones are low power radio devices, which transmit and receive radio frequency radiation in the microwave spectrum ranging from 900-1,800 MHz through an antenna used closely to the user’s head. Radiation destructs living tissue by altering structure of cell and damaging the DNA, damaging of genetic material in reproductive cells causes mutations and affecting to the next generation. The genetic database of mutation in human SRY gene has been collected and had the correlation between mutation and the occurrence of sex development disorder (translocation). However, the study focussing on SRY gene mutation to the exposure of mobile phone has not been studied, yet. This study was aimed to investigate the effect of various time exposure of mobile phone toward the characteristic of SRY gene fragments in Rattus norvegicus. Experimental research with randomized post test only control design was conducted on 20 Wistar aged 2-3 months with 200-250 grams of weight. Samples were divided into four groups, with three treatment groups based on radiation exposure time (30, 60, and 90 minutes), and one group as control group (without treatment) for 60 days. Following exposure, DNA was isolated from blood of rat, and amplified with a pair of SRY primer set. Positive DNA of SRY gene was assessed by sequencing the genes and determining the mutations. There were three single nucleotide polymorphism (SNP) of SRY gene in histidine 38 glutamine, (CAT> CAG), proline 76 threonine (CCT >ACT) and leucine 102 leucine (CTG >TTG). Long duration of radiation exposure for 90 minutes increased the risk of SRY gene mutation.ARNI AMIRERYATI DARWINAHMAD ZULVA JUNIARTOMBI & UNS Soloarticleradiation exposuresnpsry genemobile phoneBiology (General)QH301-705.5ENBiodiversitas, Vol 19, Iss 3, Pp 802-808 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	radiation exposure snp sry gene mobile phone Biology (General) QH301-705.5
spellingShingle	radiation exposure snp sry gene mobile phone Biology (General) QH301-705.5 ARNI AMIR ERYATI DARWIN AHMAD ZULVA JUNIARTO SRY gene mutation in Rattus norvegicus induced by various time exposure of mobile phone
description	Amir A, Darwin E, Juniarto AZ. 2018. Effects of mobile phone exposure to SRY gene in Rattus norvegicus. Biodiversitas 19: 802-808. Mobile phones are low power radio devices, which transmit and receive radio frequency radiation in the microwave spectrum ranging from 900-1,800 MHz through an antenna used closely to the user’s head. Radiation destructs living tissue by altering structure of cell and damaging the DNA, damaging of genetic material in reproductive cells causes mutations and affecting to the next generation. The genetic database of mutation in human SRY gene has been collected and had the correlation between mutation and the occurrence of sex development disorder (translocation). However, the study focussing on SRY gene mutation to the exposure of mobile phone has not been studied, yet. This study was aimed to investigate the effect of various time exposure of mobile phone toward the characteristic of SRY gene fragments in Rattus norvegicus. Experimental research with randomized post test only control design was conducted on 20 Wistar aged 2-3 months with 200-250 grams of weight. Samples were divided into four groups, with three treatment groups based on radiation exposure time (30, 60, and 90 minutes), and one group as control group (without treatment) for 60 days. Following exposure, DNA was isolated from blood of rat, and amplified with a pair of SRY primer set. Positive DNA of SRY gene was assessed by sequencing the genes and determining the mutations. There were three single nucleotide polymorphism (SNP) of SRY gene in histidine 38 glutamine, (CAT> CAG), proline 76 threonine (CCT >ACT) and leucine 102 leucine (CTG >TTG). Long duration of radiation exposure for 90 minutes increased the risk of SRY gene mutation.
format	article
author	ARNI AMIR ERYATI DARWIN AHMAD ZULVA JUNIARTO
author_facet	ARNI AMIR ERYATI DARWIN AHMAD ZULVA JUNIARTO
author_sort	ARNI AMIR
title	SRY gene mutation in Rattus norvegicus induced by various time exposure of mobile phone
title_short	SRY gene mutation in Rattus norvegicus induced by various time exposure of mobile phone
title_full	SRY gene mutation in Rattus norvegicus induced by various time exposure of mobile phone
title_fullStr	SRY gene mutation in Rattus norvegicus induced by various time exposure of mobile phone
title_full_unstemmed	SRY gene mutation in Rattus norvegicus induced by various time exposure of mobile phone
title_sort	sry gene mutation in rattus norvegicus induced by various time exposure of mobile phone
publisher	MBI & UNS Solo
publishDate	2018
url	https://doaj.org/article/5d84b120c99f46e8b79c62997f6d8eb1
work_keys_str_mv	AT arniamir srygenemutationinrattusnorvegicusinducedbyvarioustimeexposureofmobilephone AT eryatidarwin srygenemutationinrattusnorvegicusinducedbyvarioustimeexposureofmobilephone AT ahmadzulvajuniarto srygenemutationinrattusnorvegicusinducedbyvarioustimeexposureofmobilephone
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SRY gene mutation in Rattus norvegicus induced by various time exposure of mobile phone

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