Β-amyloid 1-42 oligomers impair function of human embryonic stem cell-derived forebrain cholinergic neurons.
Cognitive impairment in Alzheimer's disease (AD) patients is associated with a decline in the levels of growth factors, impairment of axonal transport and marked degeneration of basal forebrain cholinergic neurons (BFCNs). Neurogenesis persists in the adult human brain, and the stimulation of r...
Guardado en:
Autores principales: | Linn Wicklund, Richardson N Leão, Anne-Marie Strömberg, Malahat Mousavi, Outi Hovatta, Agneta Nordberg, Amelia Marutle |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5d86b446ea684acbba7007242dadbb1f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Lesions of the basal forebrain cholinergic system in mice disrupt idiothetic navigation.
por: Adam S Hamlin, et al.
Publicado: (2013) -
Different cholinergic cell groups in the basal forebrain regulate social interaction and social recognition memory
por: Kana Okada, et al.
Publicado: (2021) -
Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb
por: Daniel T. Case, et al.
Publicado: (2017) -
Novel AAV-based rat model of forebrain synucleinopathy shows extensive pathologies and progressive loss of cholinergic interneurons.
por: Patrick Aldrin-Kirk, et al.
Publicado: (2014) -
Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution
por: Martin Wolff, et al.
Publicado: (2017)