Β-amyloid 1-42 oligomers impair function of human embryonic stem cell-derived forebrain cholinergic neurons.

Cognitive impairment in Alzheimer's disease (AD) patients is associated with a decline in the levels of growth factors, impairment of axonal transport and marked degeneration of basal forebrain cholinergic neurons (BFCNs). Neurogenesis persists in the adult human brain, and the stimulation of r...

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Autores principales: Linn Wicklund, Richardson N Leão, Anne-Marie Strömberg, Malahat Mousavi, Outi Hovatta, Agneta Nordberg, Amelia Marutle
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/5d86b446ea684acbba7007242dadbb1f
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