The adipokine leptin modulates adventitial pericyte functions by autocrine and paracrine signalling

The adipokine leptin modulates adventitial pericyte functions by autocrine and paracrine signalling

Abstract Transplantation of adventitial pericytes (APCs) improves recovery from tissue ischemia in preclinical animal models by still unknown mechanisms. This study investigates the role of the adipokine leptin (LEP) in the regulation of human APC biological functions. Transcriptomic analysis of APC...

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Autores principales: Federica Riu, Sadie C. Slater, Eva Jover Garcia, Iker Rodriguez-Arabaolaza, Valeria Alvino, Elisa Avolio, Giuseppe Mangialardi, Andrea Cordaro, Simon Satchell, Carlo Zebele, Andrea Caporali, Gianni Angelini, Paolo Madeddu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/5d8c17ad9ff94ce4a6d3f806f84018eb
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