Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants

Maintaining protein integrity at the inner nuclear membrane (INM) is critical for eukaryotic cellular function. Here, using proximity-labeling proteomics, Huang et al. profile the INM in Arabidopsis and identify the CDC48 complex and PUX proteins as components of an INM protein degradation pathway.

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Auteurs principaux:	Aobo Huang, Yu Tang, Xuetao Shi, Min Jia, Jinheng Zhu, Xiaohan Yan, Huiqin Chen, Yangnan Gu
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/5d94d797b1214b84be331faa37e17ca3
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spelling	oai:doaj.org-article:5d94d797b1214b84be331faa37e17ca32021-12-02T16:10:52ZProximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants10.1038/s41467-020-16744-12041-1723https://doaj.org/article/5d94d797b1214b84be331faa37e17ca32020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16744-1https://doaj.org/toc/2041-1723Maintaining protein integrity at the inner nuclear membrane (INM) is critical for eukaryotic cellular function. Here, using proximity-labeling proteomics, Huang et al. profile the INM in Arabidopsis and identify the CDC48 complex and PUX proteins as components of an INM protein degradation pathway.Aobo HuangYu TangXuetao ShiMin JiaJinheng ZhuXiaohan YanHuiqin ChenYangnan GuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aobo Huang Yu Tang Xuetao Shi Min Jia Jinheng Zhu Xiaohan Yan Huiqin Chen Yangnan Gu Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants
description	Maintaining protein integrity at the inner nuclear membrane (INM) is critical for eukaryotic cellular function. Here, using proximity-labeling proteomics, Huang et al. profile the INM in Arabidopsis and identify the CDC48 complex and PUX proteins as components of an INM protein degradation pathway.
format	article
author	Aobo Huang Yu Tang Xuetao Shi Min Jia Jinheng Zhu Xiaohan Yan Huiqin Chen Yangnan Gu
author_facet	Aobo Huang Yu Tang Xuetao Shi Min Jia Jinheng Zhu Xiaohan Yan Huiqin Chen Yangnan Gu
author_sort	Aobo Huang
title	Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants
title_short	Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants
title_full	Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants
title_fullStr	Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants
title_full_unstemmed	Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants
title_sort	proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/5d94d797b1214b84be331faa37e17ca3
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Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants

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