Non-functional urinary bladder paraganglioma with negative Ga-DOTA-NOC PET/CT uptake

Abstract Background Paraganglioma of the urinary bladder is a very rare benign tumor that constitutes less than 0.5% of all bladder tumors. It can be functional and non-functional. Functional tumors present with symptoms of catecholamine excess, and non-functional tumors usually remain asymptomatic....

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Autores principales:	Linda Kalliath, D. Karthikeyan, Banumathi Ramakrishna, Gokul Kripesh, Nivedita Chandran
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	Paraganglioma Urinary bladder Non-functional Computed tomography DOTA-NOC PET/CT Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/5d9c6d18fe504742bf08aeff4007f919
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spelling	oai:doaj.org-article:5d9c6d18fe504742bf08aeff4007f9192021-11-28T12:23:21ZNon-functional urinary bladder paraganglioma with negative Ga-DOTA-NOC PET/CT uptake10.1186/s43055-021-00671-22090-4762https://doaj.org/article/5d9c6d18fe504742bf08aeff4007f9192021-11-01T00:00:00Zhttps://doi.org/10.1186/s43055-021-00671-2https://doaj.org/toc/2090-4762Abstract Background Paraganglioma of the urinary bladder is a very rare benign tumor that constitutes less than 0.5% of all bladder tumors. It can be functional and non-functional. Functional tumors present with symptoms of catecholamine excess, and non-functional tumors usually remain asymptomatic. Case presentation Here, we present a case of non-functional urinary bladder paraganglioma in a 36-year-old female who presented to us with a history of intermittent hematuria. The routine hematological and biochemical parameters were within normal limits. Diagnostic computed tomography (CT) revealed a hypervascular lesion in the urinary bladder dome with no significant uptake in gallium-68-labelled-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid peptides-NaI3-octreotide positron emission tomography (DOTA-NOC PET/CT). Histopathology and immunohistochemistry confirmed the diagnosis of paraganglioma. Conclusion We present this case because of the rare location of paraganglioma in the urinary bladder and being non-functional with low/absent somatostatin receptor expression.Linda KalliathD. KarthikeyanBanumathi RamakrishnaGokul KripeshNivedita ChandranSpringerOpenarticleParagangliomaUrinary bladderNon-functionalComputed tomographyDOTA-NOC PET/CTMedical physics. Medical radiology. Nuclear medicineR895-920ENThe Egyptian Journal of Radiology and Nuclear Medicine, Vol 52, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Paraganglioma Urinary bladder Non-functional Computed tomography DOTA-NOC PET/CT Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	Paraganglioma Urinary bladder Non-functional Computed tomography DOTA-NOC PET/CT Medical physics. Medical radiology. Nuclear medicine R895-920 Linda Kalliath D. Karthikeyan Banumathi Ramakrishna Gokul Kripesh Nivedita Chandran Non-functional urinary bladder paraganglioma with negative Ga-DOTA-NOC PET/CT uptake
description	Abstract Background Paraganglioma of the urinary bladder is a very rare benign tumor that constitutes less than 0.5% of all bladder tumors. It can be functional and non-functional. Functional tumors present with symptoms of catecholamine excess, and non-functional tumors usually remain asymptomatic. Case presentation Here, we present a case of non-functional urinary bladder paraganglioma in a 36-year-old female who presented to us with a history of intermittent hematuria. The routine hematological and biochemical parameters were within normal limits. Diagnostic computed tomography (CT) revealed a hypervascular lesion in the urinary bladder dome with no significant uptake in gallium-68-labelled-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid peptides-NaI3-octreotide positron emission tomography (DOTA-NOC PET/CT). Histopathology and immunohistochemistry confirmed the diagnosis of paraganglioma. Conclusion We present this case because of the rare location of paraganglioma in the urinary bladder and being non-functional with low/absent somatostatin receptor expression.
format	article
author	Linda Kalliath D. Karthikeyan Banumathi Ramakrishna Gokul Kripesh Nivedita Chandran
author_facet	Linda Kalliath D. Karthikeyan Banumathi Ramakrishna Gokul Kripesh Nivedita Chandran
author_sort	Linda Kalliath
title	Non-functional urinary bladder paraganglioma with negative Ga-DOTA-NOC PET/CT uptake
title_short	Non-functional urinary bladder paraganglioma with negative Ga-DOTA-NOC PET/CT uptake
title_full	Non-functional urinary bladder paraganglioma with negative Ga-DOTA-NOC PET/CT uptake
title_fullStr	Non-functional urinary bladder paraganglioma with negative Ga-DOTA-NOC PET/CT uptake
title_full_unstemmed	Non-functional urinary bladder paraganglioma with negative Ga-DOTA-NOC PET/CT uptake
title_sort	non-functional urinary bladder paraganglioma with negative ga-dota-noc pet/ct uptake
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/5d9c6d18fe504742bf08aeff4007f919
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Non-functional urinary bladder paraganglioma with negative Ga-DOTA-NOC PET/CT uptake

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