Reactive oxygen species-activated nanoprodrug of Ibuprofen for targeting traumatic brain injury in mice.

Reactive oxygen species-activated nanoprodrug of Ibuprofen for targeting traumatic brain injury in mice.

Traumatic brain injury (TBI) is an enormous public health problem, with 1.7 million new cases of TBI recorded annually by the Centers for Disease Control. However, TBI has proven to be an extremely challenging condition to treat. Here, we apply a nanoprodrug strategy in a mouse model of TBI. The nov...

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Autores principales: Morgan A Clond, Bong-Seop Lee, Jeffrey J Yu, Matthew B Singer, Takayuki Amano, Alexander W Lamb, Doniel Drazin, Babak Kateb, Eric J Ley, John S Yu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/5d9daee2bbb5491b98b4c71871410dbe
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