Reactive oxygen species-activated nanoprodrug of Ibuprofen for targeting traumatic brain injury in mice.

Reactive oxygen species-activated nanoprodrug of Ibuprofen for targeting traumatic brain injury in mice.

Traumatic brain injury (TBI) is an enormous public health problem, with 1.7 million new cases of TBI recorded annually by the Centers for Disease Control. However, TBI has proven to be an extremely challenging condition to treat. Here, we apply a nanoprodrug strategy in a mouse model of TBI. The nov...

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Bibliographic Details
Main Authors: Morgan A Clond, Bong-Seop Lee, Jeffrey J Yu, Matthew B Singer, Takayuki Amano, Alexander W Lamb, Doniel Drazin, Babak Kateb, Eric J Ley, John S Yu
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/5d9daee2bbb5491b98b4c71871410dbe
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