Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma

High-grade serous carcinomas (HGSCs) are associated with precursor lesions (STICs) in the fallopian epithelium in only half of the cases. Here the authors report the molecular analysis of HGSCs with and without associated STICs and show similar profiles supporting a common origin for all HGSCs.

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Autores principales: Jennifer Ducie, Fanny Dao, Michael Considine, Narciso Olvera, Patricia A. Shaw, Robert J. Kurman, Ie-Ming Shih, Robert A. Soslow, Leslie Cope, Douglas A. Levine
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/5da5d07cf2c84f32a259855428b75840
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spelling oai:doaj.org-article:5da5d07cf2c84f32a259855428b758402021-12-02T15:38:58ZMolecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma10.1038/s41467-017-01217-92041-1723https://doaj.org/article/5da5d07cf2c84f32a259855428b758402017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01217-9https://doaj.org/toc/2041-1723High-grade serous carcinomas (HGSCs) are associated with precursor lesions (STICs) in the fallopian epithelium in only half of the cases. Here the authors report the molecular analysis of HGSCs with and without associated STICs and show similar profiles supporting a common origin for all HGSCs.Jennifer DucieFanny DaoMichael ConsidineNarciso OlveraPatricia A. ShawRobert J. KurmanIe-Ming ShihRobert A. SoslowLeslie CopeDouglas A. LevineNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jennifer Ducie
Fanny Dao
Michael Considine
Narciso Olvera
Patricia A. Shaw
Robert J. Kurman
Ie-Ming Shih
Robert A. Soslow
Leslie Cope
Douglas A. Levine
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma
description High-grade serous carcinomas (HGSCs) are associated with precursor lesions (STICs) in the fallopian epithelium in only half of the cases. Here the authors report the molecular analysis of HGSCs with and without associated STICs and show similar profiles supporting a common origin for all HGSCs.
format article
author Jennifer Ducie
Fanny Dao
Michael Considine
Narciso Olvera
Patricia A. Shaw
Robert J. Kurman
Ie-Ming Shih
Robert A. Soslow
Leslie Cope
Douglas A. Levine
author_facet Jennifer Ducie
Fanny Dao
Michael Considine
Narciso Olvera
Patricia A. Shaw
Robert J. Kurman
Ie-Ming Shih
Robert A. Soslow
Leslie Cope
Douglas A. Levine
author_sort Jennifer Ducie
title Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma
title_short Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma
title_full Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma
title_fullStr Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma
title_full_unstemmed Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma
title_sort molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/5da5d07cf2c84f32a259855428b75840
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