Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma
High-grade serous carcinomas (HGSCs) are associated with precursor lesions (STICs) in the fallopian epithelium in only half of the cases. Here the authors report the molecular analysis of HGSCs with and without associated STICs and show similar profiles supporting a common origin for all HGSCs.
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Nature Portfolio
2017
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oai:doaj.org-article:5da5d07cf2c84f32a259855428b758402021-12-02T15:38:58ZMolecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma10.1038/s41467-017-01217-92041-1723https://doaj.org/article/5da5d07cf2c84f32a259855428b758402017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01217-9https://doaj.org/toc/2041-1723High-grade serous carcinomas (HGSCs) are associated with precursor lesions (STICs) in the fallopian epithelium in only half of the cases. Here the authors report the molecular analysis of HGSCs with and without associated STICs and show similar profiles supporting a common origin for all HGSCs.Jennifer DucieFanny DaoMichael ConsidineNarciso OlveraPatricia A. ShawRobert J. KurmanIe-Ming ShihRobert A. SoslowLeslie CopeDouglas A. LevineNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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Science Q Jennifer Ducie Fanny Dao Michael Considine Narciso Olvera Patricia A. Shaw Robert J. Kurman Ie-Ming Shih Robert A. Soslow Leslie Cope Douglas A. Levine Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma |
description |
High-grade serous carcinomas (HGSCs) are associated with precursor lesions (STICs) in the fallopian epithelium in only half of the cases. Here the authors report the molecular analysis of HGSCs with and without associated STICs and show similar profiles supporting a common origin for all HGSCs. |
format |
article |
author |
Jennifer Ducie Fanny Dao Michael Considine Narciso Olvera Patricia A. Shaw Robert J. Kurman Ie-Ming Shih Robert A. Soslow Leslie Cope Douglas A. Levine |
author_facet |
Jennifer Ducie Fanny Dao Michael Considine Narciso Olvera Patricia A. Shaw Robert J. Kurman Ie-Ming Shih Robert A. Soslow Leslie Cope Douglas A. Levine |
author_sort |
Jennifer Ducie |
title |
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma |
title_short |
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma |
title_full |
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma |
title_fullStr |
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma |
title_full_unstemmed |
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma |
title_sort |
molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/5da5d07cf2c84f32a259855428b75840 |
work_keys_str_mv |
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1718385989950373888 |