Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation

Ribosome biogenesis involves the hierarchical assembly of several proteins and RNA components. Here the authors describe a mechanism for ribosomal protein S3 incorporation into 40S ribosomal subunits that involves S3 dimerization and stepwise incorporation of two distinct S3 interaction domains coup...

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Autores principales: Valentin Mitterer, Guillaume Murat, Stéphane Réty, Magali Blaud, Lila Delbos, Tamsyn Stanborough, Helmut Bergler, Nicolas Leulliot, Dieter Kressler, Brigitte Pertschy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/5da99d0a457c4281bcffaec8f2af764d
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Sumario:Ribosome biogenesis involves the hierarchical assembly of several proteins and RNA components. Here the authors describe a mechanism for ribosomal protein S3 incorporation into 40S ribosomal subunits that involves S3 dimerization and stepwise incorporation of two distinct S3 interaction domains coupled to release of ribosomal maturation factors.