TCA cycle remodeling drives proinflammatory signaling in humans with pulmonary tuberculosis.

TCA cycle remodeling drives proinflammatory signaling in humans with pulmonary tuberculosis.

The metabolic signaling pathways that drive pathologic tissue inflammation and damage in humans with pulmonary tuberculosis (TB) are not well understood. Using combined methods in plasma high-resolution metabolomics, lipidomics and cytokine profiling from a multicohort study of humans with pulmonary...

Full description

Saved in:
Bibliographic Details
Main Authors: Jeffrey M Collins, Dean P Jones, Ashish Sharma, Manoj Khadka, Ken H Liu, Russell R Kempker, Brendan Prideaux, Kristal Maner-Smith, Nestani Tukvadze, N Sarita Shah, James C M Brust, Rafick-Pierre Sékaly, Neel R Gandhi, Henry M Blumberg, Eric A Ortlund, Thomas R Ziegler
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/5db2ee9eac9d436d93d78e7b9402b4da
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/5db2ee9eac9d436d93d78e7b9402b4da

Similar Items