Forces during cellular uptake of viruses and nanoparticles at the ventral side

Many intracellular pathogens mimic extracellular matrix motifs to specifically interact with the host membrane which may influences virus particle uptake. Here authors use single molecule tension sensors to reveal the minimal forces exerted on single virus particles and demonstrate that the uptake f...

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Autores principales:	Tina Wiegand, Marta Fratini, Felix Frey, Klaus Yserentant, Yang Liu, Eva Weber, Kornelia Galior, Julia Ohmes, Felix Braun, Dirk-Peter Herten, Steeve Boulant, Ulrich S. Schwarz, Khalid Salaita, E. Ada Cavalcanti-Adam, Joachim P. Spatz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5db88d0c54e4431a923d087d974d5bcb
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spelling	oai:doaj.org-article:5db88d0c54e4431a923d087d974d5bcb2021-12-02T15:39:27ZForces during cellular uptake of viruses and nanoparticles at the ventral side10.1038/s41467-019-13877-w2041-1723https://doaj.org/article/5db88d0c54e4431a923d087d974d5bcb2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13877-whttps://doaj.org/toc/2041-1723Many intracellular pathogens mimic extracellular matrix motifs to specifically interact with the host membrane which may influences virus particle uptake. Here authors use single molecule tension sensors to reveal the minimal forces exerted on single virus particles and demonstrate that the uptake forces scale with the adhesion energy.Tina WiegandMarta FratiniFelix FreyKlaus YserentantYang LiuEva WeberKornelia GaliorJulia OhmesFelix BraunDirk-Peter HertenSteeve BoulantUlrich S. SchwarzKhalid SalaitaE. Ada Cavalcanti-AdamJoachim P. SpatzNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tina Wiegand Marta Fratini Felix Frey Klaus Yserentant Yang Liu Eva Weber Kornelia Galior Julia Ohmes Felix Braun Dirk-Peter Herten Steeve Boulant Ulrich S. Schwarz Khalid Salaita E. Ada Cavalcanti-Adam Joachim P. Spatz Forces during cellular uptake of viruses and nanoparticles at the ventral side
description	Many intracellular pathogens mimic extracellular matrix motifs to specifically interact with the host membrane which may influences virus particle uptake. Here authors use single molecule tension sensors to reveal the minimal forces exerted on single virus particles and demonstrate that the uptake forces scale with the adhesion energy.
format	article
author	Tina Wiegand Marta Fratini Felix Frey Klaus Yserentant Yang Liu Eva Weber Kornelia Galior Julia Ohmes Felix Braun Dirk-Peter Herten Steeve Boulant Ulrich S. Schwarz Khalid Salaita E. Ada Cavalcanti-Adam Joachim P. Spatz
author_facet	Tina Wiegand Marta Fratini Felix Frey Klaus Yserentant Yang Liu Eva Weber Kornelia Galior Julia Ohmes Felix Braun Dirk-Peter Herten Steeve Boulant Ulrich S. Schwarz Khalid Salaita E. Ada Cavalcanti-Adam Joachim P. Spatz
author_sort	Tina Wiegand
title	Forces during cellular uptake of viruses and nanoparticles at the ventral side
title_short	Forces during cellular uptake of viruses and nanoparticles at the ventral side
title_full	Forces during cellular uptake of viruses and nanoparticles at the ventral side
title_fullStr	Forces during cellular uptake of viruses and nanoparticles at the ventral side
title_full_unstemmed	Forces during cellular uptake of viruses and nanoparticles at the ventral side
title_sort	forces during cellular uptake of viruses and nanoparticles at the ventral side
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/5db88d0c54e4431a923d087d974d5bcb
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Forces during cellular uptake of viruses and nanoparticles at the ventral side

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