Tolerogenic dendritic cells derived from donors with natural rubber latex allergy modulate allergen-specific T-cell responses and IgE production.

Tolerogenic dendritic cells derived from donors with natural rubber latex allergy modulate allergen-specific T-cell responses and IgE production.

Natural rubber latex (NRL; Hevea brasiliensis) allergy is an IgE-mediated reaction to latex proteins. When latex glove exposure is the main sensitizing agent, Hev b 5 is one of the major allergens. Dendritic cells (DC), the main antigen presenting cells, modulated with pharmacological agents can res...

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Autores principales: Alejandro Escobar, Adam Aguirre, María Antonieta Guzmán, Rodrigo González, Diego Catalán, Claudio Acuña-Castillo, Milton Larrondo, Mercedes López, Barbara Pesce, Jennifer Rolland, Robyn O'Hehir, Juan Carlos Aguillón
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/5dbb313d578646f19cd99d3ed6fa3750
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