Peripheral and lung resident memory T cell responses against SARS-CoV-2

Lung resident memory T (TRM) cells are important for protection from viral infection in the lungs. Here the authors use paired lung biopsy material and blood to characterize T cell responses in patients with COVID-19 over time and find persistence of antiviral lung TRM cells that might be important...

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Autores principales:	Judith Grau-Expósito, Nerea Sánchez-Gaona, Núria Massana, Marina Suppi, Antonio Astorga-Gamaza, David Perea, Joel Rosado, Anna Falcó, Cristina Kirkegaard, Ariadna Torrella, Bibiana Planas, Jordi Navarro, Paula Suanzes, Daniel Álvarez-Sierra, Alfonso Ayora, Irene Sansano, Juliana Esperalba, Cristina Andrés, Andrés Antón, Santiago Ramón y Cajal, Benito Almirante, Ricardo Pujol-Borrell, Vicenç Falcó, Joaquín Burgos, María J. Buzón, Meritxell Genescà
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5dc22db21e084436a0fa9fda65b04bc7
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spelling	oai:doaj.org-article:5dc22db21e084436a0fa9fda65b04bc72021-12-02T16:51:25ZPeripheral and lung resident memory T cell responses against SARS-CoV-210.1038/s41467-021-23333-32041-1723https://doaj.org/article/5dc22db21e084436a0fa9fda65b04bc72021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23333-3https://doaj.org/toc/2041-1723Lung resident memory T (TRM) cells are important for protection from viral infection in the lungs. Here the authors use paired lung biopsy material and blood to characterize T cell responses in patients with COVID-19 over time and find persistence of antiviral lung TRM cells that might be important to limit reinfection.Judith Grau-ExpósitoNerea Sánchez-GaonaNúria MassanaMarina SuppiAntonio Astorga-GamazaDavid PereaJoel RosadoAnna FalcóCristina KirkegaardAriadna TorrellaBibiana PlanasJordi NavarroPaula SuanzesDaniel Álvarez-SierraAlfonso AyoraIrene SansanoJuliana EsperalbaCristina AndrésAndrés AntónSantiago Ramón y CajalBenito AlmiranteRicardo Pujol-BorrellVicenç FalcóJoaquín BurgosMaría J. BuzónMeritxell GenescàNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Judith Grau-Expósito Nerea Sánchez-Gaona Núria Massana Marina Suppi Antonio Astorga-Gamaza David Perea Joel Rosado Anna Falcó Cristina Kirkegaard Ariadna Torrella Bibiana Planas Jordi Navarro Paula Suanzes Daniel Álvarez-Sierra Alfonso Ayora Irene Sansano Juliana Esperalba Cristina Andrés Andrés Antón Santiago Ramón y Cajal Benito Almirante Ricardo Pujol-Borrell Vicenç Falcó Joaquín Burgos María J. Buzón Meritxell Genescà Peripheral and lung resident memory T cell responses against SARS-CoV-2
description	Lung resident memory T (TRM) cells are important for protection from viral infection in the lungs. Here the authors use paired lung biopsy material and blood to characterize T cell responses in patients with COVID-19 over time and find persistence of antiviral lung TRM cells that might be important to limit reinfection.
format	article
author	Judith Grau-Expósito Nerea Sánchez-Gaona Núria Massana Marina Suppi Antonio Astorga-Gamaza David Perea Joel Rosado Anna Falcó Cristina Kirkegaard Ariadna Torrella Bibiana Planas Jordi Navarro Paula Suanzes Daniel Álvarez-Sierra Alfonso Ayora Irene Sansano Juliana Esperalba Cristina Andrés Andrés Antón Santiago Ramón y Cajal Benito Almirante Ricardo Pujol-Borrell Vicenç Falcó Joaquín Burgos María J. Buzón Meritxell Genescà
author_facet	Judith Grau-Expósito Nerea Sánchez-Gaona Núria Massana Marina Suppi Antonio Astorga-Gamaza David Perea Joel Rosado Anna Falcó Cristina Kirkegaard Ariadna Torrella Bibiana Planas Jordi Navarro Paula Suanzes Daniel Álvarez-Sierra Alfonso Ayora Irene Sansano Juliana Esperalba Cristina Andrés Andrés Antón Santiago Ramón y Cajal Benito Almirante Ricardo Pujol-Borrell Vicenç Falcó Joaquín Burgos María J. Buzón Meritxell Genescà
author_sort	Judith Grau-Expósito
title	Peripheral and lung resident memory T cell responses against SARS-CoV-2
title_short	Peripheral and lung resident memory T cell responses against SARS-CoV-2
title_full	Peripheral and lung resident memory T cell responses against SARS-CoV-2
title_fullStr	Peripheral and lung resident memory T cell responses against SARS-CoV-2
title_full_unstemmed	Peripheral and lung resident memory T cell responses against SARS-CoV-2
title_sort	peripheral and lung resident memory t cell responses against sars-cov-2
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5dc22db21e084436a0fa9fda65b04bc7
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Peripheral and lung resident memory T cell responses against SARS-CoV-2

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