Utilizing a reductionist model to study host-microbe interactions in intestinal inflammation

Utilizing a reductionist model to study host-microbe interactions in intestinal inflammation

Abstract Background The gut microbiome is altered in patients with inflammatory bowel disease, yet how these alterations contribute to intestinal inflammation is poorly understood. Murine models have demonstrated the importance of the microbiome in colitis since colitis fails to develop in many gene...

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Bibliographic Details
Main Authors: Amy M. Tsou, Jeremy A. Goettel, Bin Bao, Amlan Biswas, Yu Hui Kang, Naresh S. Redhu, Kaiyue Peng, Gregory G. Putzel, Jeffrey Saltzman, Ryan Kelly, Jordan Gringauz, Jared Barends, Mai Hatazaki, Sandra M. Frei, Rohini Emani, Ying Huang, Zeli Shen, James G. Fox, Jonathan N. Glickman, Bruce H. Horwitz, Scott B. Snapper
Format: article
Language:EN
Published: BMC 2021
Subjects:
Intestinal inflammation
Wiskott-Aldrich syndrome
Immune dysregulation
Gut microbiota
Defined consortium
Pathobiont
Microbial ecology
QR100-130
Online Access:https://doaj.org/article/5dc4ac88ab5f400b9de6cbbeae362a98
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