Mild catalytic defects of tert rs61748181 polymorphism affect the clinical presentation of chronic obstructive pulmonary disease

Mild catalytic defects of tert rs61748181 polymorphism affect the clinical presentation of chronic obstructive pulmonary disease

Abstract Chronic obstructive pulmonary disease (COPD) is a disorder of accelerated lung aging. Multiple pieces of evidence support that the aging biomarker short telomeres, which can be caused by mutations in telomerase reverse transcriptase (TERT), contribute to COPD pathogenesis. We hypothesized t...

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Autores principales: Jialin Xu, Diego Madureira de Oliveira, Matthew A. Trudeau, Yang Yang, Jessica J. Y. Chin, Don D. Sin, Andrew J. Sandford, Judy M. Y. Wong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
Q
Acceso en línea:https://doaj.org/article/5dc636af3f594923931f1d3f6dce1de5
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