Health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study

Martin Strassnig,1 Jaspreet S Brar,2 Rohan Ganguli31Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, FL, USA; 2Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; 3Department of Psychiatry, Centre for Addiction and Mental Health, University of Tor...

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Autores principales:	Strassnig M, Brar JS, Ganguli R
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/5dd734d0d12c48b7baac5f9303741048
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spelling	oai:doaj.org-article:5dd734d0d12c48b7baac5f93037410482021-12-02T00:22:55ZHealth-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study1178-7007https://doaj.org/article/5dd734d0d12c48b7baac5f93037410482012-10-01T00:00:00Zhttp://www.dovepress.com/health-related-quality-of-life-adiposity-and-sedentary-behavior-in-pat-a11372https://doaj.org/toc/1178-7007Martin Strassnig,1 Jaspreet S Brar,2 Rohan Ganguli31Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, FL, USA; 2Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; 3Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, CanadaObjective: To examine adiposity and sedentary behavior in relation to health-related quality of life (QoL) in patients with early schizophrenia.Methods: A cross-sectional study was used to assess adiposity by dual-energy X-ray absorptiometry scans, habitual physical activity and idle sitting time by the Short Form International Physical Activity Questionnaire, and health-related QoL by the RAND Medical Outcomes Study SF-36. QoL scores were compared with age-adjusted Canadian normative population data.Results: There were 36 participants with early schizophrenia, average age 25.1 (&plusmn;3.6). Twenty-nine (72.5%) were males. Mean illness duration was 30 (&plusmn;18) months, and mean body mass index was 28.3 (&plusmn;5). Females had higher body fat content than males (30.8 &plusmn; 6.9 vs 24.7 &plusmn; 10.6; t = &minus;2.6, df = 34; P = 0.015). Total body fat (F = 14; P = 0.001), lean body mass (F = 10.2; P = 0.001), and sedentary behavior (F = 5; P = 0.013) significantly increased across body mass index categories. Total body fat was correlated with sedentary behavior (r = 0.62; P = 0.001), and total lean body mass was negatively correlated with sedentary behavior (r = 0.39; P = 0.03). Based on SF-36 scores, participants had significantly lower physical functioning (P = 0.0034), role physical (P = 0.0003), general health (P &lt; 0.0001), vitality (P = 0.03), and physical component scores (P = 0.003) than Canadian population comparisons. Habitual sedentary behavior, more than activity or adiposity levels, was associated with health-related QoL in early schizophrenia.Conclusion: Health-related QoL is lower in early schizophrenia and is predominantly experienced in the physical domain. QoL in early schizophrenia relates to sedentary behavior more than to activity and adiposity levels.Keywords: obesity, CVD risk, activity levels, BMIStrassnig MBrar JSGanguli RDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2012, Iss default, Pp 389-394 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Strassnig M Brar JS Ganguli R Health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study
description	Martin Strassnig,1 Jaspreet S Brar,2 Rohan Ganguli31Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, FL, USA; 2Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; 3Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, CanadaObjective: To examine adiposity and sedentary behavior in relation to health-related quality of life (QoL) in patients with early schizophrenia.Methods: A cross-sectional study was used to assess adiposity by dual-energy X-ray absorptiometry scans, habitual physical activity and idle sitting time by the Short Form International Physical Activity Questionnaire, and health-related QoL by the RAND Medical Outcomes Study SF-36. QoL scores were compared with age-adjusted Canadian normative population data.Results: There were 36 participants with early schizophrenia, average age 25.1 (&plusmn;3.6). Twenty-nine (72.5%) were males. Mean illness duration was 30 (&plusmn;18) months, and mean body mass index was 28.3 (&plusmn;5). Females had higher body fat content than males (30.8 &plusmn; 6.9 vs 24.7 &plusmn; 10.6; t = &minus;2.6, df = 34; P = 0.015). Total body fat (F = 14; P = 0.001), lean body mass (F = 10.2; P = 0.001), and sedentary behavior (F = 5; P = 0.013) significantly increased across body mass index categories. Total body fat was correlated with sedentary behavior (r = 0.62; P = 0.001), and total lean body mass was negatively correlated with sedentary behavior (r = 0.39; P = 0.03). Based on SF-36 scores, participants had significantly lower physical functioning (P = 0.0034), role physical (P = 0.0003), general health (P &lt; 0.0001), vitality (P = 0.03), and physical component scores (P = 0.003) than Canadian population comparisons. Habitual sedentary behavior, more than activity or adiposity levels, was associated with health-related QoL in early schizophrenia.Conclusion: Health-related QoL is lower in early schizophrenia and is predominantly experienced in the physical domain. QoL in early schizophrenia relates to sedentary behavior more than to activity and adiposity levels.Keywords: obesity, CVD risk, activity levels, BMI
format	article
author	Strassnig M Brar JS Ganguli R
author_facet	Strassnig M Brar JS Ganguli R
author_sort	Strassnig M
title	Health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study
title_short	Health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study
title_full	Health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study
title_fullStr	Health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study
title_full_unstemmed	Health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study
title_sort	health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/5dd734d0d12c48b7baac5f9303741048
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Health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study

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