Granulocyte and monocyte/macrophage apheresis for the treatment of immune-mediated inflammatory arthropathies: case reports

Drug therapy of immune-mediated inflammatory arthropathies is not always satisfactory, and there is a risk of adverse events. Granulocyte and monocyte/macrophage apheresis (GMA) is a non-pharmacological therapeutic option that is beneficial and very well tolerated. GMA involves passing blood through...

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Autores principales: Ana Victoria Carro Martínez, Lydia Montolio Chiva, Montserrat Robustillo Villarino
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Lenguaje:EN
Publicado: BioExcel Publishing Ltd 2021
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Acceso en línea:https://doaj.org/article/5dd821439fed490c98c8d37c331e38fa
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spelling oai:doaj.org-article:5dd821439fed490c98c8d37c331e38fa2021-11-05T13:37:38ZGranulocyte and monocyte/macrophage apheresis for the treatment of immune-mediated inflammatory arthropathies: case reports10.7573/dic.2021-8-51740-4398https://doaj.org/article/5dd821439fed490c98c8d37c331e38fa2021-11-01T00:00:00Zhttps://www.drugsincontext.com/granulocyte-and-monocyte-macrophage-apheresis-for-the-treatment-of-immune-mediated-inflammatory-arthropathies:-case-reportshttps://doaj.org/toc/1740-4398Drug therapy of immune-mediated inflammatory arthropathies is not always satisfactory, and there is a risk of adverse events. Granulocyte and monocyte/macrophage apheresis (GMA) is a non-pharmacological therapeutic option that is beneficial and very well tolerated. GMA involves passing blood through a column with cellulose acetate beads to remove increased and activated myeloid lineage cells and improve the cytokine profile. The technique reduces pain and inflammation. We present four clinical reports that illustrate the clinical uses of GMA with the medical device Adacolumn® in patients with different backgrounds and immune-mediated inflammatory arthritis. The results were positive, and no adverse events were reported.Ana Victoria Carro Martínez Lydia Montolio ChivaMontserrat Robustillo VillarinoBioExcel Publishing Ltdarticledisease-modifying anti-rheumatic drugsleukapheresisnon-steroidal anti-inflammatory agentspainpsoriatic arthritisrheumatoid arthritistumour necrosis factor inhibitorsTherapeutics. PharmacologyRM1-950ENDrugs in Context, Vol 10, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic disease-modifying anti-rheumatic drugs
leukapheresis
non-steroidal anti-inflammatory agents
pain
psoriatic arthritis
rheumatoid arthritis
tumour necrosis factor inhibitors
Therapeutics. Pharmacology
RM1-950
spellingShingle disease-modifying anti-rheumatic drugs
leukapheresis
non-steroidal anti-inflammatory agents
pain
psoriatic arthritis
rheumatoid arthritis
tumour necrosis factor inhibitors
Therapeutics. Pharmacology
RM1-950
Ana Victoria Carro Martínez
Lydia Montolio Chiva
Montserrat Robustillo Villarino
Granulocyte and monocyte/macrophage apheresis for the treatment of immune-mediated inflammatory arthropathies: case reports
description Drug therapy of immune-mediated inflammatory arthropathies is not always satisfactory, and there is a risk of adverse events. Granulocyte and monocyte/macrophage apheresis (GMA) is a non-pharmacological therapeutic option that is beneficial and very well tolerated. GMA involves passing blood through a column with cellulose acetate beads to remove increased and activated myeloid lineage cells and improve the cytokine profile. The technique reduces pain and inflammation. We present four clinical reports that illustrate the clinical uses of GMA with the medical device Adacolumn® in patients with different backgrounds and immune-mediated inflammatory arthritis. The results were positive, and no adverse events were reported.
format article
author Ana Victoria Carro Martínez
Lydia Montolio Chiva
Montserrat Robustillo Villarino
author_facet Ana Victoria Carro Martínez
Lydia Montolio Chiva
Montserrat Robustillo Villarino
author_sort Ana Victoria Carro Martínez
title Granulocyte and monocyte/macrophage apheresis for the treatment of immune-mediated inflammatory arthropathies: case reports
title_short Granulocyte and monocyte/macrophage apheresis for the treatment of immune-mediated inflammatory arthropathies: case reports
title_full Granulocyte and monocyte/macrophage apheresis for the treatment of immune-mediated inflammatory arthropathies: case reports
title_fullStr Granulocyte and monocyte/macrophage apheresis for the treatment of immune-mediated inflammatory arthropathies: case reports
title_full_unstemmed Granulocyte and monocyte/macrophage apheresis for the treatment of immune-mediated inflammatory arthropathies: case reports
title_sort granulocyte and monocyte/macrophage apheresis for the treatment of immune-mediated inflammatory arthropathies: case reports
publisher BioExcel Publishing Ltd
publishDate 2021
url https://doaj.org/article/5dd821439fed490c98c8d37c331e38fa
work_keys_str_mv AT anavictoriacarromartinez granulocyteandmonocytemacrophageapheresisforthetreatmentofimmunemediatedinflammatoryarthropathiescasereports
AT lydiamontoliochiva granulocyteandmonocytemacrophageapheresisforthetreatmentofimmunemediatedinflammatoryarthropathiescasereports
AT montserratrobustillovillarino granulocyteandmonocytemacrophageapheresisforthetreatmentofimmunemediatedinflammatoryarthropathiescasereports
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