Correlation of image quality parameters with tube voltage in X-ray dark-field chest radiography: a phantom study

Abstract Grating-based X-ray dark-field imaging is a novel imaging modality with enormous technical progress during the last years. It enables the detection of microstructure impairment as in the healthy lung a strong dark-field signal is present due to the high number of air-tissue interfaces. Usin...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Andreas P. Sauter, Jana Andrejewski, Manuela Frank, Konstantin Willer, Julia Herzen, Felix Meurer, Alexander A. Fingerle, Markus R. Makowski, Franz Pfeiffer, Daniela Pfeiffer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5ddcd54a8af740cfa1c1a823cd37ee37
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5ddcd54a8af740cfa1c1a823cd37ee37
record_format	dspace
spelling	oai:doaj.org-article:5ddcd54a8af740cfa1c1a823cd37ee372021-12-02T16:14:46ZCorrelation of image quality parameters with tube voltage in X-ray dark-field chest radiography: a phantom study10.1038/s41598-021-93716-52045-2322https://doaj.org/article/5ddcd54a8af740cfa1c1a823cd37ee372021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93716-5https://doaj.org/toc/2045-2322Abstract Grating-based X-ray dark-field imaging is a novel imaging modality with enormous technical progress during the last years. It enables the detection of microstructure impairment as in the healthy lung a strong dark-field signal is present due to the high number of air-tissue interfaces. Using the experience from setups for animal imaging, first studies with a human cadaver could be performed recently. Subsequently, the first dark-field scanner for in-vivo chest imaging of humans was developed. In the current study, the optimal tube voltage for dark-field radiography of the thorax in this setup was examined using an anthropomorphic chest phantom. Tube voltages of 50–125 kVp were used while maintaining a constant dose-area-product. The resulting dark-field and attenuation radiographs were evaluated in a reader study as well as objectively in terms of contrast-to-noise ratio and signal strength. We found that the optimum tube voltage for dark-field imaging is 70 kVp as here the most favorable combination of image quality, signal strength, and sharpness is present. At this voltage, a high image quality was perceived in the reader study also for attenuation radiographs, which should be sufficient for routine imaging. The results of this study are fundamental for upcoming patient studies with living humans.Andreas P. SauterJana AndrejewskiManuela FrankKonstantin WillerJulia HerzenFelix MeurerAlexander A. FingerleMarkus R. MakowskiFranz PfeifferDaniela PfeifferNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Andreas P. Sauter Jana Andrejewski Manuela Frank Konstantin Willer Julia Herzen Felix Meurer Alexander A. Fingerle Markus R. Makowski Franz Pfeiffer Daniela Pfeiffer Correlation of image quality parameters with tube voltage in X-ray dark-field chest radiography: a phantom study
description	Abstract Grating-based X-ray dark-field imaging is a novel imaging modality with enormous technical progress during the last years. It enables the detection of microstructure impairment as in the healthy lung a strong dark-field signal is present due to the high number of air-tissue interfaces. Using the experience from setups for animal imaging, first studies with a human cadaver could be performed recently. Subsequently, the first dark-field scanner for in-vivo chest imaging of humans was developed. In the current study, the optimal tube voltage for dark-field radiography of the thorax in this setup was examined using an anthropomorphic chest phantom. Tube voltages of 50–125 kVp were used while maintaining a constant dose-area-product. The resulting dark-field and attenuation radiographs were evaluated in a reader study as well as objectively in terms of contrast-to-noise ratio and signal strength. We found that the optimum tube voltage for dark-field imaging is 70 kVp as here the most favorable combination of image quality, signal strength, and sharpness is present. At this voltage, a high image quality was perceived in the reader study also for attenuation radiographs, which should be sufficient for routine imaging. The results of this study are fundamental for upcoming patient studies with living humans.
format	article
author	Andreas P. Sauter Jana Andrejewski Manuela Frank Konstantin Willer Julia Herzen Felix Meurer Alexander A. Fingerle Markus R. Makowski Franz Pfeiffer Daniela Pfeiffer
author_facet	Andreas P. Sauter Jana Andrejewski Manuela Frank Konstantin Willer Julia Herzen Felix Meurer Alexander A. Fingerle Markus R. Makowski Franz Pfeiffer Daniela Pfeiffer
author_sort	Andreas P. Sauter
title	Correlation of image quality parameters with tube voltage in X-ray dark-field chest radiography: a phantom study
title_short	Correlation of image quality parameters with tube voltage in X-ray dark-field chest radiography: a phantom study
title_full	Correlation of image quality parameters with tube voltage in X-ray dark-field chest radiography: a phantom study
title_fullStr	Correlation of image quality parameters with tube voltage in X-ray dark-field chest radiography: a phantom study
title_full_unstemmed	Correlation of image quality parameters with tube voltage in X-ray dark-field chest radiography: a phantom study
title_sort	correlation of image quality parameters with tube voltage in x-ray dark-field chest radiography: a phantom study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5ddcd54a8af740cfa1c1a823cd37ee37
work_keys_str_mv	AT andreaspsauter correlationofimagequalityparameterswithtubevoltageinxraydarkfieldchestradiographyaphantomstudy AT janaandrejewski correlationofimagequalityparameterswithtubevoltageinxraydarkfieldchestradiographyaphantomstudy AT manuelafrank correlationofimagequalityparameterswithtubevoltageinxraydarkfieldchestradiographyaphantomstudy AT konstantinwiller correlationofimagequalityparameterswithtubevoltageinxraydarkfieldchestradiographyaphantomstudy AT juliaherzen correlationofimagequalityparameterswithtubevoltageinxraydarkfieldchestradiographyaphantomstudy AT felixmeurer correlationofimagequalityparameterswithtubevoltageinxraydarkfieldchestradiographyaphantomstudy AT alexanderafingerle correlationofimagequalityparameterswithtubevoltageinxraydarkfieldchestradiographyaphantomstudy AT markusrmakowski correlationofimagequalityparameterswithtubevoltageinxraydarkfieldchestradiographyaphantomstudy AT franzpfeiffer correlationofimagequalityparameterswithtubevoltageinxraydarkfieldchestradiographyaphantomstudy AT danielapfeiffer correlationofimagequalityparameterswithtubevoltageinxraydarkfieldchestradiographyaphantomstudy
_version_	1718384292615159808

Correlation of image quality parameters with tube voltage in X-ray dark-field chest radiography: a phantom study

Ejemplares similares