Hydroxyl radical modification of collagen type II increases its arthritogenicity and immunogenicity.

<h4>Background</h4>The oxidation of proteins by endogenously generated free radicals causes structural modifications in the molecules that lead to generation of neo-antigenic epitopes that have implications in various autoimmune disorders, including rheumatoid arthritis (RA). Collagen in...

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Autores principales: Uzma Shahab, Saheem Ahmad, Moinuddin, Kiran Dixit, Safia Habib, Khursheed Alam, Asif Ali
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/5ddd0c5ffb3c4c1abaefd8f4d17d50a3
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