Hydroxyl radical modification of collagen type II increases its arthritogenicity and immunogenicity.
<h4>Background</h4>The oxidation of proteins by endogenously generated free radicals causes structural modifications in the molecules that lead to generation of neo-antigenic epitopes that have implications in various autoimmune disorders, including rheumatoid arthritis (RA). Collagen in...
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| Auteurs principaux: | , , , , , , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2012
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| Accès en ligne: | https://doaj.org/article/5ddd0c5ffb3c4c1abaefd8f4d17d50a3 |
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