Potential repurposing of four FDA approved compounds with antiplasmodial activity identified through proteome scale computational drug discovery and in vitro assay
Abstract Malaria elimination can benefit from time and cost-efficient approaches for antimalarials such as drug repurposing. In this work, 796 DrugBank compounds were screened against 36 Plasmodium falciparum targets using QuickVina-W. Hits were selected after rescoring using GRaph Interaction Match...
Guardado en:
Autores principales: | Bakary N’tji Diallo, Tarryn Swart, Heinrich C. Hoppe, Özlem Tastan Bishop, Kevin Lobb |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5de43a6c752445bb899502702aefff11 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Can an FDA-Approved Alzheimer’s Drug Be Repurposed for Alleviating Neuronal Symptoms of Zika Virus?
por: Devika Sirohi, et al.
Publicado: (2017) -
Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats
por: Zulfiqar Z, et al.
Publicado: (2020) -
Identification of new EphA4 inhibitors by virtual screening of FDA-approved drugs
por: Shuo Gu, et al.
Publicado: (2018) -
The state of artificial intelligence-based FDA-approved medical devices and algorithms: an online database
por: Stan Benjamens, et al.
Publicado: (2020) -
A High-Throughput Screening Approach To Repurpose FDA-Approved Drugs for Bactericidal Applications against <named-content content-type="genus-species">Staphylococcus aureus</named-content> Small-Colony Variants
por: Ryan P. Trombetta, et al.
Publicado: (2018)