Cryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7 Å resolution
The conformational heterogeneity of RNA molecules makes their structure determination by X-ray crystallography and NMR challenging. Here the authors show that RNA structures can be solved by cryo-EM and present the structures of a 40 kDa SAM-IV riboswitch in the apo form and bound to its ligand S-ad...
Enregistré dans:
Auteurs principaux: | Kaiming Zhang, Shanshan Li, Kalli Kappel, Grigore Pintilie, Zhaoming Su, Tung-Chung Mou, Michael F. Schmid, Rhiju Das, Wah Chiu |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/5de6b22e3c6a4ad29f1e5dabe8c50f5e |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
SAM-VI riboswitch structure and signature for ligand discrimination
par: Aiai Sun, et autres
Publié: (2019) -
A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA
par: Dong-Jie Tang, et autres
Publié: (2020) -
High resolution imaging study of interactions between the 37 kDa/67 kDa laminin receptor and APP, beta-secretase and gamma-secretase in Alzheimer's disease.
par: Katarina Jovanovic, et autres
Publié: (2014) -
High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM
par: Mark A. Herzik, et autres
Publié: (2019) -
Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution
par: Xiao Fan, et autres
Publié: (2019)