MexY-Promoted Aminoglycoside Resistance in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>: Involvement of a Putative Proximal Binding Pocket in Aminoglycoside Recognition

ABSTRACT The resistance-nodulation-division (RND) family multidrug efflux system MexXY-OprM is a major determinant of aminoglycoside resistance in Pseudomonas aeruginosa, although the details of aminoglycoside recognition and export by MexY, the substrate-binding RND component of this efflux system,...

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Bibliographic Details
Main Authors: Calvin Ho-Fung Lau, Daniel Hughes, Keith Poole
Format: article
Language:EN
Published: American Society for Microbiology 2014
Subjects:
Online Access:https://doaj.org/article/5deec9456dac451bbf3c9a741f94382b
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