Complex multi-block analysis identifies new immunologic and genetic disease progression patterns associated with the residual β-cell function 1 year after diagnosis of type 1 diabetes.

Complex multi-block analysis identifies new immunologic and genetic disease progression patterns associated with the residual β-cell function 1 year after diagnosis of type 1 diabetes.

The purpose of the present study is to explore the progression of type 1 diabetes (T1D) in Danish children 12 months after diagnosis using Latent Factor Modelling. We include three data blocks of dynamic paraclinical biomarkers, baseline clinical characteristics and genetic profiles of diabetes rela...

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Autores principales: Marie Louise Max Andersen, Morten Arendt Rasmussen, Sven Pörksen, Jannet Svensson, Jennifer Vikre-Jørgensen, Jane Thomsen, Niels Thomas Hertel, Jesper Johannesen, Flemming Pociot, Jacob Sten Petersen, Lars Hansen, Henrik Bindesbøl Mortensen, Lotte Brøndum Nielsen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/5df222310e0c47e0a594aa9df8c59778
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https://doaj.org/article/5df222310e0c47e0a594aa9df8c59778

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