Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus

Acute antiviral functions of all nucleated cells rely on type I interferon (IFN-I) pathways triggered upon viral infection. Host responses encompass the sensing of incoming viruses, the activation of specific transcription factors that induce the transcription of IFN-I genes, the secretion of diffe...

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Autores principales:	Mickaël Bouvet, Stefanie Voigt, Takanobu Tagawa, Manuel Albanese, Yen-Fu Adam Chen, Yan Chen, Devin N. Fachko, Dagmar Pich, Christine Göbel, Rebecca L. Skalsky, Wolfgang Hammerschmidt
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/5df41ff7727d458eb1c5cf6678139f31
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:5df41ff7727d458eb1c5cf6678139f312021-11-03T18:56:10ZMultiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus2150-751110.1128/mBio.03440-20https://doaj.org/article/5df41ff7727d458eb1c5cf6678139f312021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03440-20https://doaj.org/toc/2150-7511 Acute antiviral functions of all nucleated cells rely on type I interferon (IFN-I) pathways triggered upon viral infection. Host responses encompass the sensing of incoming viruses, the activation of specific transcription factors that induce the transcription of IFN-I genes, the secretion of different IFN-I types and their recognition by the heterodimeric IFN-α/β receptor, the subsequent activation of JAK/STAT signaling pathways, and, finally, the transcription of many IFN-stimulated genes (ISGs).Mickaël BouvetStefanie VoigtTakanobu TagawaManuel AlbaneseYen-Fu Adam ChenYan ChenDevin N. FachkoDagmar PichChristine GöbelRebecca L. SkalskyWolfgang HammerschmidtAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Mickaël Bouvet Stefanie Voigt Takanobu Tagawa Manuel Albanese Yen-Fu Adam Chen Yan Chen Devin N. Fachko Dagmar Pich Christine Göbel Rebecca L. Skalsky Wolfgang Hammerschmidt Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus
description	Acute antiviral functions of all nucleated cells rely on type I interferon (IFN-I) pathways triggered upon viral infection. Host responses encompass the sensing of incoming viruses, the activation of specific transcription factors that induce the transcription of IFN-I genes, the secretion of different IFN-I types and their recognition by the heterodimeric IFN-α/β receptor, the subsequent activation of JAK/STAT signaling pathways, and, finally, the transcription of many IFN-stimulated genes (ISGs).
format	article
author	Mickaël Bouvet Stefanie Voigt Takanobu Tagawa Manuel Albanese Yen-Fu Adam Chen Yan Chen Devin N. Fachko Dagmar Pich Christine Göbel Rebecca L. Skalsky Wolfgang Hammerschmidt
author_facet	Mickaël Bouvet Stefanie Voigt Takanobu Tagawa Manuel Albanese Yen-Fu Adam Chen Yan Chen Devin N. Fachko Dagmar Pich Christine Göbel Rebecca L. Skalsky Wolfgang Hammerschmidt
author_sort	Mickaël Bouvet
title	Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus
title_short	Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus
title_full	Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus
title_fullStr	Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus
title_full_unstemmed	Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus
title_sort	multiple viral micrornas regulate interferon release and signaling early during infection with epstein-barr virus
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/5df41ff7727d458eb1c5cf6678139f31
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Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus

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