Genetic architecture of epigenetic and neuronal ageing rates in human brain regions

Studies on the ‘epigenetic clock’, a recently identified ageing biomarker, suggest that pathology might be linked to tissue-specific accelerated ageing. Here, the authors investigate ageing in the human brain and identify genetic loci associated with accelerated ageing in different brain regions....

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Autores principales:	Ake T. Lu, Eilis Hannon, Morgan E. Levine, Eileen M. Crimmins, Katie Lunnon, Jonathan Mill, Daniel H. Geschwind, Steve Horvath
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5e03eee242f245478c247604d60390ed
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spelling	oai:doaj.org-article:5e03eee242f245478c247604d60390ed2021-12-02T14:40:57ZGenetic architecture of epigenetic and neuronal ageing rates in human brain regions10.1038/ncomms153532041-1723https://doaj.org/article/5e03eee242f245478c247604d60390ed2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15353https://doaj.org/toc/2041-1723Studies on the ‘epigenetic clock’, a recently identified ageing biomarker, suggest that pathology might be linked to tissue-specific accelerated ageing. Here, the authors investigate ageing in the human brain and identify genetic loci associated with accelerated ageing in different brain regions.Ake T. LuEilis HannonMorgan E. LevineEileen M. CrimminsKatie LunnonJonathan MillDaniel H. GeschwindSteve HorvathNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ake T. Lu Eilis Hannon Morgan E. Levine Eileen M. Crimmins Katie Lunnon Jonathan Mill Daniel H. Geschwind Steve Horvath Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
description	Studies on the ‘epigenetic clock’, a recently identified ageing biomarker, suggest that pathology might be linked to tissue-specific accelerated ageing. Here, the authors investigate ageing in the human brain and identify genetic loci associated with accelerated ageing in different brain regions.
format	article
author	Ake T. Lu Eilis Hannon Morgan E. Levine Eileen M. Crimmins Katie Lunnon Jonathan Mill Daniel H. Geschwind Steve Horvath
author_facet	Ake T. Lu Eilis Hannon Morgan E. Levine Eileen M. Crimmins Katie Lunnon Jonathan Mill Daniel H. Geschwind Steve Horvath
author_sort	Ake T. Lu
title	Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
title_short	Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
title_full	Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
title_fullStr	Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
title_full_unstemmed	Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
title_sort	genetic architecture of epigenetic and neuronal ageing rates in human brain regions
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5e03eee242f245478c247604d60390ed
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Genetic architecture of epigenetic and neuronal ageing rates in human brain regions

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