Membrane Topology Mapping of the O-Antigen Flippase (Wzx), Polymerase (Wzy), and Ligase (WaaL) from <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> PAO1 Reveals Novel Domain Architectures

ABSTRACT Biosynthesis of B-band lipopolysaccharide (LPS) in Pseudomonas aeruginosa follows the Wzy-dependent pathway, requiring the integral inner membrane proteins Wzx (O-antigen [O-Ag] flippase), Wzy (O-Ag polymerase), and WaaL (O-Ag ligase). For an important first step in deciphering the mechanis...

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Bibliographic Details
Main Authors: Salim T. Islam, Véronique L. Taylor, Meng Qi, Joseph S. Lam
Format: article
Language:EN
Published: American Society for Microbiology 2010
Subjects:
Online Access:https://doaj.org/article/5e0b1ecfe66e42128b1e07e00329eef1
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