Visceral adipose tissue influences on coronary artery calcification at young and middle-age groups using computed tomography angiography

Purpose: The purpose of the study was to evaluate the impact of excessive visceral adipose tissue (VAT) on subclinical coronary atherosclerosis and coronary artery calcifications (CAC) in young and middle-age groups using multislice computed tomography. Methods: This study is a single center, cross-...

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Autores principales:	Rami M Abazid, M Obadah Kattea, Sawsan Sayed, Hanaa Saqqah, Mohammed Qintar, Osama A Smettei
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2015
Materias:	computed tomography-angiography coronary artery calcifications visceral adipose tissue Medicine R
Acceso en línea:	https://doaj.org/article/5e0b53c7ae3a485783660d4fa3feef1e
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spelling	oai:doaj.org-article:5e0b53c7ae3a485783660d4fa3feef1e2021-12-02T16:24:57ZVisceral adipose tissue influences on coronary artery calcification at young and middle-age groups using computed tomography angiography2231-07702249-446410.4103/2231-0770.160242https://doaj.org/article/5e0b53c7ae3a485783660d4fa3feef1e2015-07-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.160242https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Purpose: The purpose of the study was to evaluate the impact of excessive visceral adipose tissue (VAT) on subclinical coronary atherosclerosis and coronary artery calcifications (CAC) in young and middle-age groups using multislice computed tomography. Methods: This study is a single center, cross-sectional study. Eligible patients (n = 159), who under the age of 61 years, with chest pain and mild to moderate probability to have coronary artery disease (CAD) were enrolled. Coronary calcium score and epicardial adipose tissue (EAT) were measured at the level of the left main coronary artery while VAT was measured at the level of the iliac crest. Results: The average age was (48 ± 8 years). The mean VAT was (38 ± 21 cm 2 ) with no significant difference between men and women (38 ± 22 vs. 37 ± 19 P = 0.8) respectively. Student′s t-test analysis showed significantly higher VAT in patients with detectable CAC than patients with no CAC (48 ± 24 vs. 33 ± 18 P = 0.00002), respectively. Univariate regression analysis showed that VAT and EAT, are strong predictor for CAC (hazard ratio [HR] 1.034, 95% confidence interval [CI: 1.016-1.052]. P <0.001 and [HR] 1.344, 95% CI: [1.129-1.601] P = 0.001), respectively. Conclusion: Excessive VAT is significantly associated with positive CAC. VAT can strongly predict subclinical CAD in individuals at young and middle-age groups.Rami M AbazidM Obadah KatteaSawsan SayedHanaa SaqqahMohammed QintarOsama A SmetteiThieme Medical and Scientific Publishers Pvt. Ltd.articlecomputed tomography-angiographycoronary artery calcificationsvisceral adipose tissueMedicineRENAvicenna Journal of Medicine, Vol 05, Iss 03, Pp 83-88 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	computed tomography-angiography coronary artery calcifications visceral adipose tissue Medicine R
spellingShingle	computed tomography-angiography coronary artery calcifications visceral adipose tissue Medicine R Rami M Abazid M Obadah Kattea Sawsan Sayed Hanaa Saqqah Mohammed Qintar Osama A Smettei Visceral adipose tissue influences on coronary artery calcification at young and middle-age groups using computed tomography angiography
description	Purpose: The purpose of the study was to evaluate the impact of excessive visceral adipose tissue (VAT) on subclinical coronary atherosclerosis and coronary artery calcifications (CAC) in young and middle-age groups using multislice computed tomography. Methods: This study is a single center, cross-sectional study. Eligible patients (n = 159), who under the age of 61 years, with chest pain and mild to moderate probability to have coronary artery disease (CAD) were enrolled. Coronary calcium score and epicardial adipose tissue (EAT) were measured at the level of the left main coronary artery while VAT was measured at the level of the iliac crest. Results: The average age was (48 ± 8 years). The mean VAT was (38 ± 21 cm 2 ) with no significant difference between men and women (38 ± 22 vs. 37 ± 19 P = 0.8) respectively. Student′s t-test analysis showed significantly higher VAT in patients with detectable CAC than patients with no CAC (48 ± 24 vs. 33 ± 18 P = 0.00002), respectively. Univariate regression analysis showed that VAT and EAT, are strong predictor for CAC (hazard ratio [HR] 1.034, 95% confidence interval [CI: 1.016-1.052]. P <0.001 and [HR] 1.344, 95% CI: [1.129-1.601] P = 0.001), respectively. Conclusion: Excessive VAT is significantly associated with positive CAC. VAT can strongly predict subclinical CAD in individuals at young and middle-age groups.
format	article
author	Rami M Abazid M Obadah Kattea Sawsan Sayed Hanaa Saqqah Mohammed Qintar Osama A Smettei
author_facet	Rami M Abazid M Obadah Kattea Sawsan Sayed Hanaa Saqqah Mohammed Qintar Osama A Smettei
author_sort	Rami M Abazid
title	Visceral adipose tissue influences on coronary artery calcification at young and middle-age groups using computed tomography angiography
title_short	Visceral adipose tissue influences on coronary artery calcification at young and middle-age groups using computed tomography angiography
title_full	Visceral adipose tissue influences on coronary artery calcification at young and middle-age groups using computed tomography angiography
title_fullStr	Visceral adipose tissue influences on coronary artery calcification at young and middle-age groups using computed tomography angiography
title_full_unstemmed	Visceral adipose tissue influences on coronary artery calcification at young and middle-age groups using computed tomography angiography
title_sort	visceral adipose tissue influences on coronary artery calcification at young and middle-age groups using computed tomography angiography
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2015
url	https://doaj.org/article/5e0b53c7ae3a485783660d4fa3feef1e
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Visceral adipose tissue influences on coronary artery calcification at young and middle-age groups using computed tomography angiography

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