Role of Hakai in m6A modification pathway in Drosophila

Drosophila m6A writer complex regulates alternative splicing of the Sex-lethal gene. Here the authors show that a potential E3 ligase Hakai interacts with the fly m6A writer complex and that m6A level is reduced in Hakai mutant flies.

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Autores principales:	Yanhua Wang, Lifeng Zhang, Hang Ren, Lijuan Ma, Jian Guo, Decai Mao, Zhongwen Lu, Lijun Lu, Dong Yan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5e0dc5d5e01143d99afed20b1554968e
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spelling	oai:doaj.org-article:5e0dc5d5e01143d99afed20b1554968e2021-12-02T14:30:27ZRole of Hakai in m6A modification pathway in Drosophila10.1038/s41467-021-22424-52041-1723https://doaj.org/article/5e0dc5d5e01143d99afed20b1554968e2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22424-5https://doaj.org/toc/2041-1723Drosophila m6A writer complex regulates alternative splicing of the Sex-lethal gene. Here the authors show that a potential E3 ligase Hakai interacts with the fly m6A writer complex and that m6A level is reduced in Hakai mutant flies.Yanhua WangLifeng ZhangHang RenLijuan MaJian GuoDecai MaoZhongwen LuLijun LuDong YanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yanhua Wang Lifeng Zhang Hang Ren Lijuan Ma Jian Guo Decai Mao Zhongwen Lu Lijun Lu Dong Yan Role of Hakai in m6A modification pathway in Drosophila
description	Drosophila m6A writer complex regulates alternative splicing of the Sex-lethal gene. Here the authors show that a potential E3 ligase Hakai interacts with the fly m6A writer complex and that m6A level is reduced in Hakai mutant flies.
format	article
author	Yanhua Wang Lifeng Zhang Hang Ren Lijuan Ma Jian Guo Decai Mao Zhongwen Lu Lijun Lu Dong Yan
author_facet	Yanhua Wang Lifeng Zhang Hang Ren Lijuan Ma Jian Guo Decai Mao Zhongwen Lu Lijun Lu Dong Yan
author_sort	Yanhua Wang
title	Role of Hakai in m6A modification pathway in Drosophila
title_short	Role of Hakai in m6A modification pathway in Drosophila
title_full	Role of Hakai in m6A modification pathway in Drosophila
title_fullStr	Role of Hakai in m6A modification pathway in Drosophila
title_full_unstemmed	Role of Hakai in m6A modification pathway in Drosophila
title_sort	role of hakai in m6a modification pathway in drosophila
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5e0dc5d5e01143d99afed20b1554968e
work_keys_str_mv	AT yanhuawang roleofhakaiinm6amodificationpathwayindrosophila AT lifengzhang roleofhakaiinm6amodificationpathwayindrosophila AT hangren roleofhakaiinm6amodificationpathwayindrosophila AT lijuanma roleofhakaiinm6amodificationpathwayindrosophila AT jianguo roleofhakaiinm6amodificationpathwayindrosophila AT decaimao roleofhakaiinm6amodificationpathwayindrosophila AT zhongwenlu roleofhakaiinm6amodificationpathwayindrosophila AT lijunlu roleofhakaiinm6amodificationpathwayindrosophila AT dongyan roleofhakaiinm6amodificationpathwayindrosophila
_version_	1718391192752750592

Role of Hakai in m6A modification pathway in Drosophila

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