Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer’s disease transgenic mouse model

Abstract Alzheimer’s disease (AD) is a devastating neurodegenerative disorder with no disease-modifying treatment. AD progression is characterized by cognitive decline, neuroinflammation, and accumulation of amyloid-beta (Aβ) and neurofibrillary tangles in the brain, leading to neuronal and glial dy...

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Autores principales: Jackie K. Y. Lau, Min Tian, Yang Shen, Shun-Fat Lau, Wing-Yu Fu, Amy K. Y. Fu, Nancy Y. Ip
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5e145d10ba444c13a408a1dd72b67715
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