Infiltrating basal cell carcinoma: a stellate peri-tumor dermatoscopy pattern as a clue to diagnosis

Background: Infiltrating basal cell carcinoma (BCC) has associated features that may be readily identified using dermatoscopy. Objective: Investigate a stellate dermatoscopy pattern extending from the peripheral margin of infiltrating BCC. Methods: A total of 741 consecutive cases of BCC wer...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	John H. Pyne, Paul Fishburn, Anthony Dicker, Michael David
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2015
Materias:	basal cell carcinoma dermatoscopy dermoscopy: infiltrating skin cancer vessels Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/5e168e8a92fd42fb946b1c448eb1f492
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5e168e8a92fd42fb946b1c448eb1f492
record_format	dspace
spelling	oai:doaj.org-article:5e168e8a92fd42fb946b1c448eb1f4922021-11-17T08:31:47ZInfiltrating basal cell carcinoma: a stellate peri-tumor dermatoscopy pattern as a clue to diagnosis10.5826/dpc.0502a022160-9381https://doaj.org/article/5e168e8a92fd42fb946b1c448eb1f4922015-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/737https://doaj.org/toc/2160-9381 Background: Infiltrating basal cell carcinoma (BCC) has associated features that may be readily identified using dermatoscopy. Objective: Investigate a stellate dermatoscopy pattern extending from the peripheral margin of infiltrating BCC. Methods: A total of 741 consecutive cases of BCC were assessed retrospectively using non-polarized dermatoscopy. Following histopathologic examination, cases were categorized into six different BCC subtypes. Infiltrating cases numbered 107. This stellate feature was defined as a geometric star shaped pattern extending outwards from the circumferential peripheral edge of the tumor, and identified by white lines, vessels or uneven skin surface morphology. The percentages of infiltrating subtype within the tumor mass and tumor depth were compared, with and without the stellate pattern. Results: Infiltrating BCC displayed the stellate pattern more than other BCC subtypes. Concordance between the two observers was almost perfect for white lines: Kappa coefficient of 0.87 (95% CI: 0.0.79-0.95) P<0.01 and substantial for vessels: Kappa coefficient of 0.71 95% CI: 0.59-0.84) P<0.01. Folds were only recorded in infiltrating cases (n=3). Compared to other BCC subtypes the stellate pattern had a sensitivity of 31.7% and specificity of 94.1%. A higher mean fraction of the tumor mass containing infiltrating subtype was found when comparing stellate pattern observed to stellate pattern not observed (P<0.01). No statistically significant association was found between the tumor depth with and without the stellate pattern. Conclusion: This study found a higher incidence of the stellate pattern within infiltrating BCC compared to the other BCC subtypes. As the percentage of the infiltrating subtype within the tumors increased the incidence of the stellate pattern also increased. John H. PynePaul FishburnAnthony DickerMichael DavidMattioli1885articlebasal cell carcinomadermatoscopydermoscopy: infiltratingskin cancervesselsDermatologyRL1-803ENDermatology Practical & Conceptual (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	basal cell carcinoma dermatoscopy dermoscopy: infiltrating skin cancer vessels Dermatology RL1-803
spellingShingle	basal cell carcinoma dermatoscopy dermoscopy: infiltrating skin cancer vessels Dermatology RL1-803 John H. Pyne Paul Fishburn Anthony Dicker Michael David Infiltrating basal cell carcinoma: a stellate peri-tumor dermatoscopy pattern as a clue to diagnosis
description	Background: Infiltrating basal cell carcinoma (BCC) has associated features that may be readily identified using dermatoscopy. Objective: Investigate a stellate dermatoscopy pattern extending from the peripheral margin of infiltrating BCC. Methods: A total of 741 consecutive cases of BCC were assessed retrospectively using non-polarized dermatoscopy. Following histopathologic examination, cases were categorized into six different BCC subtypes. Infiltrating cases numbered 107. This stellate feature was defined as a geometric star shaped pattern extending outwards from the circumferential peripheral edge of the tumor, and identified by white lines, vessels or uneven skin surface morphology. The percentages of infiltrating subtype within the tumor mass and tumor depth were compared, with and without the stellate pattern. Results: Infiltrating BCC displayed the stellate pattern more than other BCC subtypes. Concordance between the two observers was almost perfect for white lines: Kappa coefficient of 0.87 (95% CI: 0.0.79-0.95) P<0.01 and substantial for vessels: Kappa coefficient of 0.71 95% CI: 0.59-0.84) P<0.01. Folds were only recorded in infiltrating cases (n=3). Compared to other BCC subtypes the stellate pattern had a sensitivity of 31.7% and specificity of 94.1%. A higher mean fraction of the tumor mass containing infiltrating subtype was found when comparing stellate pattern observed to stellate pattern not observed (P<0.01). No statistically significant association was found between the tumor depth with and without the stellate pattern. Conclusion: This study found a higher incidence of the stellate pattern within infiltrating BCC compared to the other BCC subtypes. As the percentage of the infiltrating subtype within the tumors increased the incidence of the stellate pattern also increased.
format	article
author	John H. Pyne Paul Fishburn Anthony Dicker Michael David
author_facet	John H. Pyne Paul Fishburn Anthony Dicker Michael David
author_sort	John H. Pyne
title	Infiltrating basal cell carcinoma: a stellate peri-tumor dermatoscopy pattern as a clue to diagnosis
title_short	Infiltrating basal cell carcinoma: a stellate peri-tumor dermatoscopy pattern as a clue to diagnosis
title_full	Infiltrating basal cell carcinoma: a stellate peri-tumor dermatoscopy pattern as a clue to diagnosis
title_fullStr	Infiltrating basal cell carcinoma: a stellate peri-tumor dermatoscopy pattern as a clue to diagnosis
title_full_unstemmed	Infiltrating basal cell carcinoma: a stellate peri-tumor dermatoscopy pattern as a clue to diagnosis
title_sort	infiltrating basal cell carcinoma: a stellate peri-tumor dermatoscopy pattern as a clue to diagnosis
publisher	Mattioli1885
publishDate	2015
url	https://doaj.org/article/5e168e8a92fd42fb946b1c448eb1f492
work_keys_str_mv	AT johnhpyne infiltratingbasalcellcarcinomaastellateperitumordermatoscopypatternasacluetodiagnosis AT paulfishburn infiltratingbasalcellcarcinomaastellateperitumordermatoscopypatternasacluetodiagnosis AT anthonydicker infiltratingbasalcellcarcinomaastellateperitumordermatoscopypatternasacluetodiagnosis AT michaeldavid infiltratingbasalcellcarcinomaastellateperitumordermatoscopypatternasacluetodiagnosis
_version_	1718425672577187840

Infiltrating basal cell carcinoma: a stellate peri-tumor dermatoscopy pattern as a clue to diagnosis

Ejemplares similares