Prevalence, comorbidity and heritability of hoarding symptoms in adolescence: a population based twin study in 15-year olds.

<h4>Background</h4>Hoarding Disorder (HD) is often assumed to be an 'old age' problem, but many individuals diagnosed with HD retrospectively report first experiencing symptoms in childhood or adolescence. We examined the prevalence, comorbidity and etiology of hoarding symptom...

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Autores principales: Volen Z Ivanov, David Mataix-Cols, Eva Serlachius, Paul Lichtenstein, Henrik Anckarsäter, Zheng Chang, Clara Hellner Gumpert, Sebastian Lundström, Niklas Långström, Christian Rück
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Publicado: Public Library of Science (PLoS) 2013
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spelling oai:doaj.org-article:5e1a1e6d33974f069d95a03ac029ef002021-11-18T07:37:53ZPrevalence, comorbidity and heritability of hoarding symptoms in adolescence: a population based twin study in 15-year olds.1932-620310.1371/journal.pone.0069140https://doaj.org/article/5e1a1e6d33974f069d95a03ac029ef002013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23874893/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Hoarding Disorder (HD) is often assumed to be an 'old age' problem, but many individuals diagnosed with HD retrospectively report first experiencing symptoms in childhood or adolescence. We examined the prevalence, comorbidity and etiology of hoarding symptoms in adolescence.<h4>Methods</h4>To determine the presence of clinically significant hoarding symptoms, a population-based sample of 15-year old twins (N = 3,974) completed the Hoarding Rating Scale-Self Report. Co-occurring Obsessive Compulsive Disorder (OCD), Autism Spectrum Disorders (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) were estimated from parental report. Model-fitting analyses divided hoarding symptom scores into additive genetic, shared, and non-shared environmental effects.<h4>Results</h4>The prevalence of clinically significant hoarding symptoms was 2% (95% CI 1.6-2.5%), with a significantly higher prevalence in girls than boys. Exclusion of the clutter criterion (as adolescents do not have control over their environment) increased the prevalence rate to 3.7% (95% CI 3.1-4.3%). Excessive acquisition was reported by 30-40% among those with clinically significant hoarding symptoms. The prevalence of co-occurring OCD (2.9%), ASD (2.9%) and ADHD (10.0%) was comparable in hoarding and non-hoarding teenagers. Model-fitting analyses suggested that, in boys, additive genetic (32%; 95% CI 13-44%) and non-shared environmental effects accounted for most of the variance. In contrast, among girls, shared and non-shared environmental effects explained most of the variance, while additive genetic factors played a negligible role.<h4>Conclusions</h4>Hoarding symptoms are relatively prevalent in adolescents, particularly in girls, and cause distress and/or impairment. Hoarding was rarely associated with other common neurodevelopmental disorders, supporting its DSM-5 status as an independent diagnosis. The relative importance of genetic and shared environmental factors for hoarding differed across sexes. The findings are suggestive of dynamic developmental genetic and environmental effects operating from adolescence onto adulthood.Volen Z IvanovDavid Mataix-ColsEva SerlachiusPaul LichtensteinHenrik AnckarsäterZheng ChangClara Hellner GumpertSebastian LundströmNiklas LångströmChristian RückPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 7, p e69140 (2013)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Volen Z Ivanov
David Mataix-Cols
Eva Serlachius
Paul Lichtenstein
Henrik Anckarsäter
Zheng Chang
Clara Hellner Gumpert
Sebastian Lundström
Niklas Långström
Christian Rück
Prevalence, comorbidity and heritability of hoarding symptoms in adolescence: a population based twin study in 15-year olds.
description <h4>Background</h4>Hoarding Disorder (HD) is often assumed to be an 'old age' problem, but many individuals diagnosed with HD retrospectively report first experiencing symptoms in childhood or adolescence. We examined the prevalence, comorbidity and etiology of hoarding symptoms in adolescence.<h4>Methods</h4>To determine the presence of clinically significant hoarding symptoms, a population-based sample of 15-year old twins (N = 3,974) completed the Hoarding Rating Scale-Self Report. Co-occurring Obsessive Compulsive Disorder (OCD), Autism Spectrum Disorders (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) were estimated from parental report. Model-fitting analyses divided hoarding symptom scores into additive genetic, shared, and non-shared environmental effects.<h4>Results</h4>The prevalence of clinically significant hoarding symptoms was 2% (95% CI 1.6-2.5%), with a significantly higher prevalence in girls than boys. Exclusion of the clutter criterion (as adolescents do not have control over their environment) increased the prevalence rate to 3.7% (95% CI 3.1-4.3%). Excessive acquisition was reported by 30-40% among those with clinically significant hoarding symptoms. The prevalence of co-occurring OCD (2.9%), ASD (2.9%) and ADHD (10.0%) was comparable in hoarding and non-hoarding teenagers. Model-fitting analyses suggested that, in boys, additive genetic (32%; 95% CI 13-44%) and non-shared environmental effects accounted for most of the variance. In contrast, among girls, shared and non-shared environmental effects explained most of the variance, while additive genetic factors played a negligible role.<h4>Conclusions</h4>Hoarding symptoms are relatively prevalent in adolescents, particularly in girls, and cause distress and/or impairment. Hoarding was rarely associated with other common neurodevelopmental disorders, supporting its DSM-5 status as an independent diagnosis. The relative importance of genetic and shared environmental factors for hoarding differed across sexes. The findings are suggestive of dynamic developmental genetic and environmental effects operating from adolescence onto adulthood.
format article
author Volen Z Ivanov
David Mataix-Cols
Eva Serlachius
Paul Lichtenstein
Henrik Anckarsäter
Zheng Chang
Clara Hellner Gumpert
Sebastian Lundström
Niklas Långström
Christian Rück
author_facet Volen Z Ivanov
David Mataix-Cols
Eva Serlachius
Paul Lichtenstein
Henrik Anckarsäter
Zheng Chang
Clara Hellner Gumpert
Sebastian Lundström
Niklas Långström
Christian Rück
author_sort Volen Z Ivanov
title Prevalence, comorbidity and heritability of hoarding symptoms in adolescence: a population based twin study in 15-year olds.
title_short Prevalence, comorbidity and heritability of hoarding symptoms in adolescence: a population based twin study in 15-year olds.
title_full Prevalence, comorbidity and heritability of hoarding symptoms in adolescence: a population based twin study in 15-year olds.
title_fullStr Prevalence, comorbidity and heritability of hoarding symptoms in adolescence: a population based twin study in 15-year olds.
title_full_unstemmed Prevalence, comorbidity and heritability of hoarding symptoms in adolescence: a population based twin study in 15-year olds.
title_sort prevalence, comorbidity and heritability of hoarding symptoms in adolescence: a population based twin study in 15-year olds.
publisher Public Library of Science (PLoS)
publishDate 2013
url https://doaj.org/article/5e1a1e6d33974f069d95a03ac029ef00
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