A narrative review of psoriasis and multiple sclerosis: links and risks

Annika S Silfvast-Kaiser,1 Katie B Homan,2 Bobbak Mansouri3–51Department of Dermatology, Baylor Scott and White, Dallas, TX, USA; 2Department of Dermatology, Baylor Scott and White Medical Center, Temple, TX, USA; 3Austin Institute for Clinical Research, Pflugerville, TX, USA; 4Sanova Derm...

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Autores principales: Silfvast-Kaiser AS, Homan KB, Mansouri B
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2019
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Acceso en línea:https://doaj.org/article/5e21b2fa886d40449d151e02422e9cc8
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Sumario:Annika S Silfvast-Kaiser,1 Katie B Homan,2 Bobbak Mansouri3–51Department of Dermatology, Baylor Scott and White, Dallas, TX, USA; 2Department of Dermatology, Baylor Scott and White Medical Center, Temple, TX, USA; 3Austin Institute for Clinical Research, Pflugerville, TX, USA; 4Sanova Dermatology – Pflugerville, Pflugerville, TX, USA; 5U.S. Dermatology Partners - Tyler, TX, USACorrespondence: Bobbak MansouriUS Dermatology Partners - Tyler, TX 1367 Dominion Plaza, Pflugerville, TX 75703, USAEmail bobbak.mansouri@gmail.comAbstract: The association of psoriasis (PsO) with other autoimmune and autoinflammatory diseases has long been a topic of interest. Although previous studies have attempted to clarify the specific relationship between PsO and multiple sclerosis (MS), it remains obscure, with limited and conflicting evidence regarding a link between the two entities. Herein, we review the etiology, pathogenesis, and treatment of each disease and present the available literature to-date regarding a possible relationship between PsO and MS. We conclude that further study is necessary to discern whether there may be a significant relationship between PsO and MS. In the meantime, clinicians may find it appropriate to screen for MS in patients with PsO, allowing for timely referral to a neurologist should it be necessary.Keywords: psoriasis, multiple sclerosis, incidence, prevalence, links, risk factors