Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue

van Haaften et al. show numerical-experimental approach to reconstruct the graft–host response. They interrogate the mechanoregulation in dialysis grafts to solve the disturbed shear stress problem, which can be a cause of neointimal hyperplasia in blood vessels and grafts.

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Autores principales:	Eline E. van Haaften, Sjeng Quicken, Wouter Huberts, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/5e25773dc2fe4f8d9d8f013fae7a9000
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spelling	oai:doaj.org-article:5e25773dc2fe4f8d9d8f013fae7a90002021-12-02T15:36:12ZComputationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue10.1038/s42003-021-02065-62399-3642https://doaj.org/article/5e25773dc2fe4f8d9d8f013fae7a90002021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02065-6https://doaj.org/toc/2399-3642van Haaften et al. show numerical-experimental approach to reconstruct the graft–host response. They interrogate the mechanoregulation in dialysis grafts to solve the disturbed shear stress problem, which can be a cause of neointimal hyperplasia in blood vessels and grafts.Eline E. van HaaftenSjeng QuickenWouter HubertsCarlijn V. C. BoutenNicholas A. KurniawanNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Eline E. van Haaften Sjeng Quicken Wouter Huberts Carlijn V. C. Bouten Nicholas A. Kurniawan Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue
description	van Haaften et al. show numerical-experimental approach to reconstruct the graft–host response. They interrogate the mechanoregulation in dialysis grafts to solve the disturbed shear stress problem, which can be a cause of neointimal hyperplasia in blood vessels and grafts.
format	article
author	Eline E. van Haaften Sjeng Quicken Wouter Huberts Carlijn V. C. Bouten Nicholas A. Kurniawan
author_facet	Eline E. van Haaften Sjeng Quicken Wouter Huberts Carlijn V. C. Bouten Nicholas A. Kurniawan
author_sort	Eline E. van Haaften
title	Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue
title_short	Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue
title_full	Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue
title_fullStr	Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue
title_full_unstemmed	Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue
title_sort	computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5e25773dc2fe4f8d9d8f013fae7a9000
work_keys_str_mv	AT elineevanhaaften computationallyguidedinvitrovasculargrowthmodelrevealscausallinkbetweenflowoscillationsanddisorganizedneotissue AT sjengquicken computationallyguidedinvitrovasculargrowthmodelrevealscausallinkbetweenflowoscillationsanddisorganizedneotissue AT wouterhuberts computationallyguidedinvitrovasculargrowthmodelrevealscausallinkbetweenflowoscillationsanddisorganizedneotissue AT carlijnvcbouten computationallyguidedinvitrovasculargrowthmodelrevealscausallinkbetweenflowoscillationsanddisorganizedneotissue AT nicholasakurniawan computationallyguidedinvitrovasculargrowthmodelrevealscausallinkbetweenflowoscillationsanddisorganizedneotissue
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Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue

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