Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery

Synthetic RNA-based circuits allow for gene regulation without the risk of mutagenesis. Here the authors demonstrate a Caliciviral VPg-based Translational activator which allows translational activation of synthetic mRNAs.

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Main Authors:	Hideyuki Nakanishi, Hirohide Saito
Format:	article
Language:	EN
Published:	Nature Portfolio 2020
Subjects:	Science Q
Online Access:	https://doaj.org/article/5e30d568b49f4600b7bcbcb6d289726f
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spelling	oai:doaj.org-article:5e30d568b49f4600b7bcbcb6d289726f2021-12-02T13:35:01ZCaliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery10.1038/s41467-020-15061-x2041-1723https://doaj.org/article/5e30d568b49f4600b7bcbcb6d289726f2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15061-xhttps://doaj.org/toc/2041-1723Synthetic RNA-based circuits allow for gene regulation without the risk of mutagenesis. Here the authors demonstrate a Caliciviral VPg-based Translational activator which allows translational activation of synthetic mRNAs.Hideyuki NakanishiHirohide SaitoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hideyuki Nakanishi Hirohide Saito Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery
description	Synthetic RNA-based circuits allow for gene regulation without the risk of mutagenesis. Here the authors demonstrate a Caliciviral VPg-based Translational activator which allows translational activation of synthetic mRNAs.
format	article
author	Hideyuki Nakanishi Hirohide Saito
author_facet	Hideyuki Nakanishi Hirohide Saito
author_sort	Hideyuki Nakanishi
title	Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery
title_short	Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery
title_full	Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery
title_fullStr	Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery
title_full_unstemmed	Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery
title_sort	caliciviral protein-based artificial translational activator for mammalian gene circuits with rna-only delivery
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/5e30d568b49f4600b7bcbcb6d289726f
work_keys_str_mv	AT hideyukinakanishi caliciviralproteinbasedartificialtranslationalactivatorformammaliangenecircuitswithrnaonlydelivery AT hirohidesaito caliciviralproteinbasedartificialtranslationalactivatorformammaliangenecircuitswithrnaonlydelivery
_version_	1718392738381037568

Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery

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