Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery

Synthetic RNA-based circuits allow for gene regulation without the risk of mutagenesis. Here the authors demonstrate a Caliciviral VPg-based Translational activator which allows translational activation of synthetic mRNAs.

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Auteurs principaux: Hideyuki Nakanishi, Hirohide Saito
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/5e30d568b49f4600b7bcbcb6d289726f
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