The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice

The role of the gut microbiota in hepatic lipid metabolism is controversial and incompletely understood. Here the authors perform multi-omics analyses of altered lipid metabolic processes in germ-free and specific pathogen-free mice, revealing how the gut microbiota affects hepatic fatty acid desatu...

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Autores principales: Alida Kindt, Gerhard Liebisch, Thomas Clavel, Dirk Haller, Gabriele Hörmannsperger, Hongsup Yoon, Daniela Kolmeder, Alexander Sigruener, Sabrina Krautbauer, Claudine Seeliger, Alexandra Ganzha, Sabine Schweizer, Rosalie Morisset, Till Strowig, Hannelore Daniel, Dominic Helm, Bernhard Küster, Jan Krumsiek, Josef Ecker
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5e32139272c34b6ea782afa0b254afc8
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spelling oai:doaj.org-article:5e32139272c34b6ea782afa0b254afc82021-12-02T16:56:52ZThe gut microbiota promotes hepatic fatty acid desaturation and elongation in mice10.1038/s41467-018-05767-42041-1723https://doaj.org/article/5e32139272c34b6ea782afa0b254afc82018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05767-4https://doaj.org/toc/2041-1723The role of the gut microbiota in hepatic lipid metabolism is controversial and incompletely understood. Here the authors perform multi-omics analyses of altered lipid metabolic processes in germ-free and specific pathogen-free mice, revealing how the gut microbiota affects hepatic fatty acid desaturation and elongation.Alida KindtGerhard LiebischThomas ClavelDirk HallerGabriele HörmannspergerHongsup YoonDaniela KolmederAlexander SigruenerSabrina KrautbauerClaudine SeeligerAlexandra GanzhaSabine SchweizerRosalie MorissetTill StrowigHannelore DanielDominic HelmBernhard KüsterJan KrumsiekJosef EckerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alida Kindt
Gerhard Liebisch
Thomas Clavel
Dirk Haller
Gabriele Hörmannsperger
Hongsup Yoon
Daniela Kolmeder
Alexander Sigruener
Sabrina Krautbauer
Claudine Seeliger
Alexandra Ganzha
Sabine Schweizer
Rosalie Morisset
Till Strowig
Hannelore Daniel
Dominic Helm
Bernhard Küster
Jan Krumsiek
Josef Ecker
The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
description The role of the gut microbiota in hepatic lipid metabolism is controversial and incompletely understood. Here the authors perform multi-omics analyses of altered lipid metabolic processes in germ-free and specific pathogen-free mice, revealing how the gut microbiota affects hepatic fatty acid desaturation and elongation.
format article
author Alida Kindt
Gerhard Liebisch
Thomas Clavel
Dirk Haller
Gabriele Hörmannsperger
Hongsup Yoon
Daniela Kolmeder
Alexander Sigruener
Sabrina Krautbauer
Claudine Seeliger
Alexandra Ganzha
Sabine Schweizer
Rosalie Morisset
Till Strowig
Hannelore Daniel
Dominic Helm
Bernhard Küster
Jan Krumsiek
Josef Ecker
author_facet Alida Kindt
Gerhard Liebisch
Thomas Clavel
Dirk Haller
Gabriele Hörmannsperger
Hongsup Yoon
Daniela Kolmeder
Alexander Sigruener
Sabrina Krautbauer
Claudine Seeliger
Alexandra Ganzha
Sabine Schweizer
Rosalie Morisset
Till Strowig
Hannelore Daniel
Dominic Helm
Bernhard Küster
Jan Krumsiek
Josef Ecker
author_sort Alida Kindt
title The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
title_short The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
title_full The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
title_fullStr The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
title_full_unstemmed The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
title_sort gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/5e32139272c34b6ea782afa0b254afc8
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