Bidirectional asymmetry in the neurovisceral communication for the cardiovascular control: New insights

The cardiovascular control involves a bidirectional functional connection between the brain and heart. We hypothesize that this connection could be extended to other organs using endocrine and autonomic nervous systems (ANS) as communication pathways. This implies a neuroendocrine interaction contro...

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Autores principales:	Prieto I, Segarra AB, Martinez-Canamero M, De Gasparo M, Zorad S, Ramirez-Sanchez M
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2017
Materias:	neuroendocrine interaction asymmetry blood pressure renin-angiotensin system neuropeptidases angiotensinases Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/5e361c36558243c0a1094eb1e16ce1fd
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spelling	oai:doaj.org-article:5e361c36558243c0a1094eb1e16ce1fd2021-12-02T17:49:19ZBidirectional asymmetry in the neurovisceral communication for the cardiovascular control: New insights1336-032910.1515/enr-2017-0017https://doaj.org/article/5e361c36558243c0a1094eb1e16ce1fd2017-07-01T00:00:00Zhttps://doi.org/10.1515/enr-2017-0017https://doaj.org/toc/1336-0329The cardiovascular control involves a bidirectional functional connection between the brain and heart. We hypothesize that this connection could be extended to other organs using endocrine and autonomic nervous systems (ANS) as communication pathways. This implies a neuroendocrine interaction controlling particularly the cardiovascular function where the enzymatic cascade of the renin-angiotensin system (RAS) plays an essential role. It acts not only through its classic endocrine connection but also the ANS. In addition, the brain is functionally, anatomically, and neurochemically asymmetric. Moreover, this asymmetry goes even beyond the brain and it includes both sides of the peripheral nervous and neuroendocrine systems. We revised the available information and analyze the asymmetrical neuroendocrine bidirectional interaction for the cardiovascular control. Negative and positive correlations involving the RAS have been observed between brain, heart, kidney, gut, and plasma in physiologic and pathologic conditions. The central role of the peptides and enzymes of the RAS within this neurovisceral communication, as well as the importance of the asymmetrical distribution of the various RAS components in the pathologies involving this connection, are particularly discussed. In conclusion, there are numerous evidences supporting the existence of a neurovisceral connection with multiorgan involvement that controls, among others, the cardiovascular function. This connection is asymmetrically organized.Prieto ISegarra ABMartinez-Canamero MDe Gasparo MZorad SRamirez-Sanchez MSciendoarticleneuroendocrine interactionasymmetryblood pressurerenin-angiotensin systemneuropeptidasesangiotensinasesDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 51, Iss 3, Pp 157-167 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	neuroendocrine interaction asymmetry blood pressure renin-angiotensin system neuropeptidases angiotensinases Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	neuroendocrine interaction asymmetry blood pressure renin-angiotensin system neuropeptidases angiotensinases Diseases of the endocrine glands. Clinical endocrinology RC648-665 Prieto I Segarra AB Martinez-Canamero M De Gasparo M Zorad S Ramirez-Sanchez M Bidirectional asymmetry in the neurovisceral communication for the cardiovascular control: New insights
description	The cardiovascular control involves a bidirectional functional connection between the brain and heart. We hypothesize that this connection could be extended to other organs using endocrine and autonomic nervous systems (ANS) as communication pathways. This implies a neuroendocrine interaction controlling particularly the cardiovascular function where the enzymatic cascade of the renin-angiotensin system (RAS) plays an essential role. It acts not only through its classic endocrine connection but also the ANS. In addition, the brain is functionally, anatomically, and neurochemically asymmetric. Moreover, this asymmetry goes even beyond the brain and it includes both sides of the peripheral nervous and neuroendocrine systems. We revised the available information and analyze the asymmetrical neuroendocrine bidirectional interaction for the cardiovascular control. Negative and positive correlations involving the RAS have been observed between brain, heart, kidney, gut, and plasma in physiologic and pathologic conditions. The central role of the peptides and enzymes of the RAS within this neurovisceral communication, as well as the importance of the asymmetrical distribution of the various RAS components in the pathologies involving this connection, are particularly discussed. In conclusion, there are numerous evidences supporting the existence of a neurovisceral connection with multiorgan involvement that controls, among others, the cardiovascular function. This connection is asymmetrically organized.
format	article
author	Prieto I Segarra AB Martinez-Canamero M De Gasparo M Zorad S Ramirez-Sanchez M
author_facet	Prieto I Segarra AB Martinez-Canamero M De Gasparo M Zorad S Ramirez-Sanchez M
author_sort	Prieto I
title	Bidirectional asymmetry in the neurovisceral communication for the cardiovascular control: New insights
title_short	Bidirectional asymmetry in the neurovisceral communication for the cardiovascular control: New insights
title_full	Bidirectional asymmetry in the neurovisceral communication for the cardiovascular control: New insights
title_fullStr	Bidirectional asymmetry in the neurovisceral communication for the cardiovascular control: New insights
title_full_unstemmed	Bidirectional asymmetry in the neurovisceral communication for the cardiovascular control: New insights
title_sort	bidirectional asymmetry in the neurovisceral communication for the cardiovascular control: new insights
publisher	Sciendo
publishDate	2017
url	https://doaj.org/article/5e361c36558243c0a1094eb1e16ce1fd
work_keys_str_mv	AT prietoi bidirectionalasymmetryintheneurovisceralcommunicationforthecardiovascularcontrolnewinsights AT segarraab bidirectionalasymmetryintheneurovisceralcommunicationforthecardiovascularcontrolnewinsights AT martinezcanamerom bidirectionalasymmetryintheneurovisceralcommunicationforthecardiovascularcontrolnewinsights AT degasparom bidirectionalasymmetryintheneurovisceralcommunicationforthecardiovascularcontrolnewinsights AT zorads bidirectionalasymmetryintheneurovisceralcommunicationforthecardiovascularcontrolnewinsights AT ramirezsanchezm bidirectionalasymmetryintheneurovisceralcommunicationforthecardiovascularcontrolnewinsights
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Bidirectional asymmetry in the neurovisceral communication for the cardiovascular control: New insights

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