Serine-71 phosphorylation of Rac1 modulates downstream signaling.

The Rho GTPases Rac1 and Cdc42 regulate a variety of cellular functions by signaling to different signal pathways. It is believed that the presence of a specific effector at the location of GTPase activation determines the route of downstream signaling. We previously reported about EGF-induced Ser-7...

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Autores principales: Janett Schwarz, Julia Proff, Anika Hävemeier, Markus Ladwein, Klemens Rottner, Britta Barlag, Andreas Pich, Helma Tatge, Ingo Just, Ralf Gerhard
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/5e44924797cc488a8fbeaeddd3ecf374
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