Rosmarinic acid suppresses tau phosphorylation and cognitive decline by downregulating the JNK signaling pathway

Abstract Rosmarinic acid (RA), a polyphenol found in Lamiaceae herbs, is a candidate of preventive ingredients against Alzheimer’s disease (AD) as it potently suppresses the aggregation of amyloid β (Aβ); however, the effect of RA on tau phosphorylation and cognitive dysfunction remains unclear. The...

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Autores principales: So Yamamoto, Tomoko Kayama, Moeko Noguchi-Shinohara, Tsuyoshi Hamaguchi, Masahito Yamada, Keiko Abe, Shoko Kobayashi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5e455a803e4e47eca76785f5f73fcc6e
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