Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection

Drugs inhibiting virulence factors of bacterial pathogens are under development. Here, Thänertet al. analyse the transcriptomes of host and pathogen during Staphylococcus aureusinfection of two mouse strains, and show that virulence determinants are differentially expressed in different mouse strain...

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Autores principales: Robert Thänert, Oliver Goldmann, Andreas Beineke, Eva Medina
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/5e49170ea1ff42948166598323b9bb35
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Sumario:Drugs inhibiting virulence factors of bacterial pathogens are under development. Here, Thänertet al. analyse the transcriptomes of host and pathogen during Staphylococcus aureusinfection of two mouse strains, and show that virulence determinants are differentially expressed in different mouse strains.