Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection

Drugs inhibiting virulence factors of bacterial pathogens are under development. Here, Thänertet al. analyse the transcriptomes of host and pathogen during Staphylococcus aureusinfection of two mouse strains, and show that virulence determinants are differentially expressed in different mouse strain...

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Autores principales:	Robert Thänert, Oliver Goldmann, Andreas Beineke, Eva Medina
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5e49170ea1ff42948166598323b9bb35
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spelling	oai:doaj.org-article:5e49170ea1ff42948166598323b9bb352021-12-02T14:42:11ZHost-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection10.1038/ncomms142682041-1723https://doaj.org/article/5e49170ea1ff42948166598323b9bb352017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14268https://doaj.org/toc/2041-1723Drugs inhibiting virulence factors of bacterial pathogens are under development. Here, Thänertet al. analyse the transcriptomes of host and pathogen during Staphylococcus aureusinfection of two mouse strains, and show that virulence determinants are differentially expressed in different mouse strains.Robert ThänertOliver GoldmannAndreas BeinekeEva MedinaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Robert Thänert Oliver Goldmann Andreas Beineke Eva Medina Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection
description	Drugs inhibiting virulence factors of bacterial pathogens are under development. Here, Thänertet al. analyse the transcriptomes of host and pathogen during Staphylococcus aureusinfection of two mouse strains, and show that virulence determinants are differentially expressed in different mouse strains.
format	article
author	Robert Thänert Oliver Goldmann Andreas Beineke Eva Medina
author_facet	Robert Thänert Oliver Goldmann Andreas Beineke Eva Medina
author_sort	Robert Thänert
title	Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection
title_short	Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection
title_full	Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection
title_fullStr	Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection
title_full_unstemmed	Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection
title_sort	host-inherent variability influences the transcriptional response of staphylococcus aureus during in vivo infection
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5e49170ea1ff42948166598323b9bb35
work_keys_str_mv	AT robertthanert hostinherentvariabilityinfluencesthetranscriptionalresponseofstaphylococcusaureusduringinvivoinfection AT olivergoldmann hostinherentvariabilityinfluencesthetranscriptionalresponseofstaphylococcusaureusduringinvivoinfection AT andreasbeineke hostinherentvariabilityinfluencesthetranscriptionalresponseofstaphylococcusaureusduringinvivoinfection AT evamedina hostinherentvariabilityinfluencesthetranscriptionalresponseofstaphylococcusaureusduringinvivoinfection
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Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection

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