Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?

There is an increasing awareness of the prevalence of iron deficiency in patients with heart failure (HF), and its contributory role in the morbidity and mortality of HF. Iron is a trace element necessary for cells due to its capacity to transport oxygen and electrons. The prevalence of iron deficie...

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Autores principales:	Nicole Ebner, Stephan von Haehling
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2019
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/5e4dfbc6c9514990b371af8aa2c59614
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spelling	oai:doaj.org-article:5e4dfbc6c9514990b371af8aa2c596142021-12-04T16:01:54ZWhy is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?10.15420/cfr.2019.9.22057-75592057-7540https://doaj.org/article/5e4dfbc6c9514990b371af8aa2c596142019-11-01T00:00:00Zhttps://www.cfrjournal.com/articles/Iron-Deficiency-Comorbidity-Heart-Failurehttps://doaj.org/toc/2057-7540https://doaj.org/toc/2057-7559There is an increasing awareness of the prevalence of iron deficiency in patients with heart failure (HF), and its contributory role in the morbidity and mortality of HF. Iron is a trace element necessary for cells due to its capacity to transport oxygen and electrons. The prevalence of iron deficiency increases with the severity of HF. For a long time the influence of iron deficiency was underestimated, especially in terms of worsening of cardiovascular diseases and developing anaemia. In recent years, studies with intravenous iron agents in patients with iron deficiency and HF showed new insights into the improvement of iron therapy. Additionally, experimental studies supporting the understanding of iron metabolism and the resulting pathophysiological pathways of iron have been carried out. The aim of this mini review is to highlight why iron deficiency is recognised as an important comorbidity in HF.Nicole EbnerStephan von HaehlingRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENCardiac Failure Review , Vol 5, Iss 3, Pp 173-175 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Nicole Ebner Stephan von Haehling Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?
description	There is an increasing awareness of the prevalence of iron deficiency in patients with heart failure (HF), and its contributory role in the morbidity and mortality of HF. Iron is a trace element necessary for cells due to its capacity to transport oxygen and electrons. The prevalence of iron deficiency increases with the severity of HF. For a long time the influence of iron deficiency was underestimated, especially in terms of worsening of cardiovascular diseases and developing anaemia. In recent years, studies with intravenous iron agents in patients with iron deficiency and HF showed new insights into the improvement of iron therapy. Additionally, experimental studies supporting the understanding of iron metabolism and the resulting pathophysiological pathways of iron have been carried out. The aim of this mini review is to highlight why iron deficiency is recognised as an important comorbidity in HF.
format	article
author	Nicole Ebner Stephan von Haehling
author_facet	Nicole Ebner Stephan von Haehling
author_sort	Nicole Ebner
title	Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?
title_short	Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?
title_full	Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?
title_fullStr	Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?
title_full_unstemmed	Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?
title_sort	why is iron deficiency recognised as an important comorbidity in heart failure?
publisher	Radcliffe Medical Media
publishDate	2019
url	https://doaj.org/article/5e4dfbc6c9514990b371af8aa2c59614
work_keys_str_mv	AT nicoleebner whyisirondeficiencyrecognisedasanimportantcomorbidityinheartfailure AT stephanvonhaehling whyisirondeficiencyrecognisedasanimportantcomorbidityinheartfailure
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Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?

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