Sight-threatening optic neuropathy is associated with paranasal lymphoma

Takahiko Hayashi1, Ken Watanabe2, Yukio Tsuura3, Gengo Tsuji4, Shingo Koyama4, Jun Yoshigi4, Naoko Hirata1, Shin Yamane1, Yasuhito Iizima5, Shigeo Toyota6, Satoshi Takeuchi11Department of Ophthalmology, Yokosuka Kyosai Hospital, Japan; 2Department of Hematology, Graduate School of Medicine, Tokyo Me...

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Autores principales:	Takahiko Hayashi, Ken Watanabe, Yukio Tsuura, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/5e5ffeb2f95b47d9ba6fe13530784491
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spelling	oai:doaj.org-article:5e5ffeb2f95b47d9ba6fe135307844912021-12-02T06:21:21ZSight-threatening optic neuropathy is associated with paranasal lymphoma1177-54671177-5483https://doaj.org/article/5e5ffeb2f95b47d9ba6fe135307844912010-03-01T00:00:00Zhttp://www.dovepress.com/sight-threatening-optic-neuropathy-is-associated-with-paranasal-lympho-a4054https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Takahiko Hayashi1, Ken Watanabe2, Yukio Tsuura3, Gengo Tsuji4, Shingo Koyama4, Jun Yoshigi4, Naoko Hirata1, Shin Yamane1, Yasuhito Iizima5, Shigeo Toyota6, Satoshi Takeuchi11Department of Ophthalmology, Yokosuka Kyosai Hospital, Japan; 2Department of Hematology, Graduate School of Medicine, Tokyo Medical and Dental University, Japan; 3Department of Pathology, Yokosuka Kyosai Hospital, Japan; 4Department of Radiology, Yokosuka Kyosai Hospital, Japan; 5Department of Ophthalmology, Yokohama City University, Japan; 6Department of Internal Medicine, Yokosuka Kyosai Hospital, JapanAbstract: Malignant lymphoma around the orbit is very rare. We present a rare case of optic neuropathy caused by lymphoma. A 61-year-old Japanese woman was referred to our hospital for evaluation of idiopathic optic neuropathy affecting her right eye. The patient was treated with steroid pulse therapy (methyl-predonisolone 1 g daily for 3 days) with a presumed diagnosis of idiopathic optic neuritis. After she had been switched to oral steroid therapy, endoscopic sinus surgery had been performed, which revealed diffuse large B cell lymphoma of the ethmoidal sinus. Although R-CHOP therapy was immediately started, prolonged optic nerve compression resulted in irreversible blindness. Accordingly, patients with suspected idiopathic optic neuritis should be carefully assessed when they show a poor response, and imaging of the orbits and brain should always be done for initial diagnosis because they may have compression by a tumor.Keywords: optic neuropathy, malignant lymphoma, paranasal lymphoma, rhinogenic optic neuropathy Takahiko HayashiKen WatanabeYukio Tsuuraet alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 143-146 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Takahiko Hayashi Ken Watanabe Yukio Tsuura et al Sight-threatening optic neuropathy is associated with paranasal lymphoma
description	Takahiko Hayashi1, Ken Watanabe2, Yukio Tsuura3, Gengo Tsuji4, Shingo Koyama4, Jun Yoshigi4, Naoko Hirata1, Shin Yamane1, Yasuhito Iizima5, Shigeo Toyota6, Satoshi Takeuchi11Department of Ophthalmology, Yokosuka Kyosai Hospital, Japan; 2Department of Hematology, Graduate School of Medicine, Tokyo Medical and Dental University, Japan; 3Department of Pathology, Yokosuka Kyosai Hospital, Japan; 4Department of Radiology, Yokosuka Kyosai Hospital, Japan; 5Department of Ophthalmology, Yokohama City University, Japan; 6Department of Internal Medicine, Yokosuka Kyosai Hospital, JapanAbstract: Malignant lymphoma around the orbit is very rare. We present a rare case of optic neuropathy caused by lymphoma. A 61-year-old Japanese woman was referred to our hospital for evaluation of idiopathic optic neuropathy affecting her right eye. The patient was treated with steroid pulse therapy (methyl-predonisolone 1 g daily for 3 days) with a presumed diagnosis of idiopathic optic neuritis. After she had been switched to oral steroid therapy, endoscopic sinus surgery had been performed, which revealed diffuse large B cell lymphoma of the ethmoidal sinus. Although R-CHOP therapy was immediately started, prolonged optic nerve compression resulted in irreversible blindness. Accordingly, patients with suspected idiopathic optic neuritis should be carefully assessed when they show a poor response, and imaging of the orbits and brain should always be done for initial diagnosis because they may have compression by a tumor.Keywords: optic neuropathy, malignant lymphoma, paranasal lymphoma, rhinogenic optic neuropathy
format	article
author	Takahiko Hayashi Ken Watanabe Yukio Tsuura et al
author_facet	Takahiko Hayashi Ken Watanabe Yukio Tsuura et al
author_sort	Takahiko Hayashi
title	Sight-threatening optic neuropathy is associated with paranasal lymphoma
title_short	Sight-threatening optic neuropathy is associated with paranasal lymphoma
title_full	Sight-threatening optic neuropathy is associated with paranasal lymphoma
title_fullStr	Sight-threatening optic neuropathy is associated with paranasal lymphoma
title_full_unstemmed	Sight-threatening optic neuropathy is associated with paranasal lymphoma
title_sort	sight-threatening optic neuropathy is associated with paranasal lymphoma
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/5e5ffeb2f95b47d9ba6fe13530784491
work_keys_str_mv	AT takahikohayashi sightthreateningopticneuropathyisassociatedwithparanasallymphoma AT kenwatanabe sightthreateningopticneuropathyisassociatedwithparanasallymphoma AT yukiotsuura sightthreateningopticneuropathyisassociatedwithparanasallymphoma AT etal sightthreateningopticneuropathyisassociatedwithparanasallymphoma
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Sight-threatening optic neuropathy is associated with paranasal lymphoma

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