Inner lumen proteins stabilize doublet microtubules in cilia and flagella

Microtubules in cilia are sufficiently stable to withstand the beating motion, but how they are stabilized while serving as tracks for intraflagellar transport and axonemal dyneins remains unknown. Here authors identify two microtubule inner proteins, FAP45 and FAP52, which stabilize the ciliary axo...

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Autores principales:	Mikito Owa, Takayuki Uchihashi, Haru-aki Yanagisawa, Takashi Yamano, Hiro Iguchi, Hideya Fukuzawa, Ken-ichi Wakabayashi, Toshio Ando, Masahide Kikkawa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5e612bec25a646c4a808060c4891ba90
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spelling	oai:doaj.org-article:5e612bec25a646c4a808060c4891ba902021-12-02T17:32:54ZInner lumen proteins stabilize doublet microtubules in cilia and flagella10.1038/s41467-019-09051-x2041-1723https://doaj.org/article/5e612bec25a646c4a808060c4891ba902019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09051-xhttps://doaj.org/toc/2041-1723Microtubules in cilia are sufficiently stable to withstand the beating motion, but how they are stabilized while serving as tracks for intraflagellar transport and axonemal dyneins remains unknown. Here authors identify two microtubule inner proteins, FAP45 and FAP52, which stabilize the ciliary axonemes in Chlamydomonas.Mikito OwaTakayuki UchihashiHaru-aki YanagisawaTakashi YamanoHiro IguchiHideya FukuzawaKen-ichi WakabayashiToshio AndoMasahide KikkawaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mikito Owa Takayuki Uchihashi Haru-aki Yanagisawa Takashi Yamano Hiro Iguchi Hideya Fukuzawa Ken-ichi Wakabayashi Toshio Ando Masahide Kikkawa Inner lumen proteins stabilize doublet microtubules in cilia and flagella
description	Microtubules in cilia are sufficiently stable to withstand the beating motion, but how they are stabilized while serving as tracks for intraflagellar transport and axonemal dyneins remains unknown. Here authors identify two microtubule inner proteins, FAP45 and FAP52, which stabilize the ciliary axonemes in Chlamydomonas.
format	article
author	Mikito Owa Takayuki Uchihashi Haru-aki Yanagisawa Takashi Yamano Hiro Iguchi Hideya Fukuzawa Ken-ichi Wakabayashi Toshio Ando Masahide Kikkawa
author_facet	Mikito Owa Takayuki Uchihashi Haru-aki Yanagisawa Takashi Yamano Hiro Iguchi Hideya Fukuzawa Ken-ichi Wakabayashi Toshio Ando Masahide Kikkawa
author_sort	Mikito Owa
title	Inner lumen proteins stabilize doublet microtubules in cilia and flagella
title_short	Inner lumen proteins stabilize doublet microtubules in cilia and flagella
title_full	Inner lumen proteins stabilize doublet microtubules in cilia and flagella
title_fullStr	Inner lumen proteins stabilize doublet microtubules in cilia and flagella
title_full_unstemmed	Inner lumen proteins stabilize doublet microtubules in cilia and flagella
title_sort	inner lumen proteins stabilize doublet microtubules in cilia and flagella
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/5e612bec25a646c4a808060c4891ba90
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_version_	1718380122310967296

Inner lumen proteins stabilize doublet microtubules in cilia and flagella

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