Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions
Allele and genotype frequencies of 5 polymorphisms were studied in healthy population in Transbaikalian region. High percent of spontaneous and inductive aggregation were observed in subjects with three or more mutant allele (р < 0,05). These subjects developed maximum radius of aggregates only i...
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| Formato: | article |
| Lenguaje: | RU |
| Publicado: |
Scientific Сentre for Family Health and Human Reproduction Problems
2013
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/5e612c53b9fe4dfa8e13ae32ad3c7f29 |
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| Sumario: | Allele and genotype frequencies of 5 polymorphisms were studied in healthy population in Transbaikalian region. High percent of spontaneous and inductive aggregation were observed in subjects with three or more mutant allele (р < 0,05). These subjects developed maximum radius of aggregates only in spontaneous -1,7 ± 0,4 opt.un. (р < 0,05) and collagen-induced aggregation - 7,6 ± 2,5 opt.un. (р < 0,05). |
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