Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions

Allele and genotype frequencies of 5 polymorphisms were studied in healthy population in Transbaikalian region. High percent of spontaneous and inductive aggregation were observed in subjects with three or more mutant allele (р < 0,05). These subjects developed maximum radius of aggregates only i...

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Autor principal: N. N. Strambovskaya
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2013
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Acceso en línea:https://doaj.org/article/5e612c53b9fe4dfa8e13ae32ad3c7f29
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spelling oai:doaj.org-article:5e612c53b9fe4dfa8e13ae32ad3c7f292021-11-23T06:14:29ZPlatelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions2541-94202587-9596https://doaj.org/article/5e612c53b9fe4dfa8e13ae32ad3c7f292013-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1682https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Allele and genotype frequencies of 5 polymorphisms were studied in healthy population in Transbaikalian region. High percent of spontaneous and inductive aggregation were observed in subjects with three or more mutant allele (р < 0,05). These subjects developed maximum radius of aggregates only in spontaneous -1,7 ± 0,4 opt.un. (р < 0,05) and collagen-induced aggregation - 7,6 ± 2,5 opt.un. (р < 0,05).N. N. StrambovskayaScientific Сentre for Family Health and Human Reproduction Problemsarticleplateletsaggregate of plateletplatelet receptionsgene polymorphismpopulation geneticsScienceQRUActa Biomedica Scientifica, Vol 0, Iss 6, Pp 65-70 (2013)
institution DOAJ
collection DOAJ
language RU
topic platelets
aggregate of platelet
platelet receptions
gene polymorphism
population genetics
Science
Q
spellingShingle platelets
aggregate of platelet
platelet receptions
gene polymorphism
population genetics
Science
Q
N. N. Strambovskaya
Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions
description Allele and genotype frequencies of 5 polymorphisms were studied in healthy population in Transbaikalian region. High percent of spontaneous and inductive aggregation were observed in subjects with three or more mutant allele (р < 0,05). These subjects developed maximum radius of aggregates only in spontaneous -1,7 ± 0,4 opt.un. (р < 0,05) and collagen-induced aggregation - 7,6 ± 2,5 opt.un. (р < 0,05).
format article
author N. N. Strambovskaya
author_facet N. N. Strambovskaya
author_sort N. N. Strambovskaya
title Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions
title_short Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions
title_full Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions
title_fullStr Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions
title_full_unstemmed Platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions
title_sort platelet functions in healthy persons with genetic polymorphisms gpia(с807т), gpiiia(т1565с), gpipa(с434т), p2ry12(н1/н2), selp(-g1087a) platelet receptions
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2013
url https://doaj.org/article/5e612c53b9fe4dfa8e13ae32ad3c7f29
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