Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals

Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals

Previously it was shown that an N-terminal tau fragment (NT1) measured in plasma can differentiate individuals with Alzheimer’s disease from healthy controls. Here the authors show that plasma levels of NT1 can associate with future cognitive decline in cognitively normal elderly individuals.

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Autores principales: Jasmeer P. Chhatwal, Aaron P. Schultz, Yifan Dang, Beth Ostaszewski, Lei Liu, Hyun-Sik Yang, Keith A. Johnson, Reisa A. Sperling, Dennis J. Selkoe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/5e6552d7e8ff43c699163b028de8f4b4
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