A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells

Ex vivo methods of circulating tumor cell (CTC) isolation use small blood volumes, limiting sensitivity and introducing analytical inaccuracies. The authors describe a proof-of-concept study of an in vivo aphaeresis system that continuously collects CTCs from a peripheral vein over several hours.

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Autores principales: Tae Hyun Kim, Yang Wang, C. Ryan Oliver, Douglas H. Thamm, Laura Cooling, Costanza Paoletti, Kaylee J. Smith, Sunitha Nagrath, Daniel F. Hayes
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/5e6e1cbabb7f40a58693713234fb08b1
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spelling oai:doaj.org-article:5e6e1cbabb7f40a58693713234fb08b12021-12-02T17:01:36ZA temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells10.1038/s41467-019-09439-92041-1723https://doaj.org/article/5e6e1cbabb7f40a58693713234fb08b12019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09439-9https://doaj.org/toc/2041-1723Ex vivo methods of circulating tumor cell (CTC) isolation use small blood volumes, limiting sensitivity and introducing analytical inaccuracies. The authors describe a proof-of-concept study of an in vivo aphaeresis system that continuously collects CTCs from a peripheral vein over several hours.Tae Hyun KimYang WangC. Ryan OliverDouglas H. ThammLaura CoolingCostanza PaolettiKaylee J. SmithSunitha NagrathDaniel F. HayesNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tae Hyun Kim
Yang Wang
C. Ryan Oliver
Douglas H. Thamm
Laura Cooling
Costanza Paoletti
Kaylee J. Smith
Sunitha Nagrath
Daniel F. Hayes
A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells
description Ex vivo methods of circulating tumor cell (CTC) isolation use small blood volumes, limiting sensitivity and introducing analytical inaccuracies. The authors describe a proof-of-concept study of an in vivo aphaeresis system that continuously collects CTCs from a peripheral vein over several hours.
format article
author Tae Hyun Kim
Yang Wang
C. Ryan Oliver
Douglas H. Thamm
Laura Cooling
Costanza Paoletti
Kaylee J. Smith
Sunitha Nagrath
Daniel F. Hayes
author_facet Tae Hyun Kim
Yang Wang
C. Ryan Oliver
Douglas H. Thamm
Laura Cooling
Costanza Paoletti
Kaylee J. Smith
Sunitha Nagrath
Daniel F. Hayes
author_sort Tae Hyun Kim
title A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells
title_short A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells
title_full A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells
title_fullStr A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells
title_full_unstemmed A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells
title_sort temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/5e6e1cbabb7f40a58693713234fb08b1
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